| 正品大黄中34种化学成分的高效液相色谱法定量分析 |
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| 引用本文： | 郑俊华,西泽信,山岸乔,西冈五夫,金子光,三桥博,楼之岑.正品大黄中34种化学成分的高效液相色谱法定量分析[J].北京大学学报(医学版),1989(1). |
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| 作者姓名： | 郑俊华 西泽信 山岸乔 西冈五夫 金子光 三桥博 楼之岑 |
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| 作者单位： | 北京医科大学生药学教研室
(郑俊华)，北海道大学药学部
(西泽信，金子光)，北海道立卫生研究所
(山岸乔)，九州大学药学部
(西冈五夫)，日本津村顺天堂津村研究所
(三桥博)，北京医科大学生药学教研室(楼之岑) |
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| 摘 要： | 本文首次报道了应用高效液相色谱仪测定大黄中34种化学成分的方法,并用此法测定三种正品大黄:唐古特大黄(林棵黄)Rheum tanguticum Maxim.ex Balf.,掌叶大黄R.palmatum L.和药用大黄(马蹄大黄)R.foficianle Baill.根和根茎中34种化学成分的含量,包括5种游离蒽醌、12种蒽甙、5种芪甙、3种苯丁酮甙、2种萘酚甙和7种鞣质化合物。结果表明:唐古特大黄含有除蒽醌及其单糖甙外的其他成分最多;其次为掌叶大黄,但掌叶大黄含有的游离蒽醌及其单糖甙最多;药用大黄的根茎,各种成分的含量均最少。
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| 关 键 词： | 唐古特大黄 掌叶大黄 药用大黄 高效液相色谱法 大黄化学成分定量分析 |
HPLC DETERMINATION OF 34 CHEMICAL CONSTITUENTS IN THREE OFFICIAL RHUBARBS |
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| Institution: | Department of Pharmacognosy Zheng Junhua,et al |
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| Abstract: | 34 chemical constituents of rhubarb rhizomes derived from Rheum tanguticum Maxim, ex Balf., R. palmatum L. and R. officinale Baill. were determined by a HPLC method. The constituents determined included 5 free anthraquinones, 12 anthraglucosides, 5 stilbenes, 3 phenylbutanones and one of its glucoside, 2 naphthol glucosides and 7 tanninoids. The results showed that rhizome of R. tanguticm has the highest content of these constituents except free anthraquinones and their monoglucosides, rhizome of R. palmatum is the next but has the highest content of free anthraquinones and their monoglucosides, rhizome of R. officinale has the lowest content of most constituents. |
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| Keywords: | Rheum tanguticum R palmatum R officinale High performance liquid chromatography Determination of chemical constituents in rhubarb |
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