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立体定向神经核团毁损治疗帕金森病患者运动功能障碍
引用本文:林恒州,张猛,纪涛.立体定向神经核团毁损治疗帕金森病患者运动功能障碍[J].中国医药导刊,2011,13(8):1336-1337.
作者姓名:林恒州  张猛  纪涛
作者单位:深圳市第二人民医院神经外科,深圳,518035
摘    要:目的:探讨立体定向神经核团毁损治疗帕金森病患者运动功能障碍研究。方法:本研究采用立体定向神经核团毁损术治疗110例帕金森病患者,僵直型9例,震颤型15例,僵直震颤型86例。结果:110例患者冶疗前帕金森病评定量晴(UPDRS)运动评分,"开"状态是(52.5±6.8),"关"状态是(61.3±6.0);治疗后7天UPDRS运动评分,"开"状态是(22.1±7.0),"关"状态是(23.7±7.2),差异具有统计学意义(P<0.01)。结论:立体定向神经核团毁损术能够显著改善帕金森病患者的各项运动功能障碍。

关 键 词:立体定向  神经核团毁损  帕金森病  运动功能障碍

Stereotactic Nuclei Lesion for Treating Dysfunction in Patients with Parkinson's Disease
Lin Heng-zhou,Zhang Meng,Ji Tao.Stereotactic Nuclei Lesion for Treating Dysfunction in Patients with Parkinson's Disease[J].Chinese Journal of Medicinal Guide,2011,13(8):1336-1337.
Authors:Lin Heng-zhou  Zhang Meng  Ji Tao
Institution:(Neurosurgery Department,Shenzhen Second People’s Hospital,Shenzhen 518035,China)
Abstract:Objective:To evaluate the research on stereotactic nuclei lesion for treatomg motor dysfunction in Parkinson’s disease. Methods:There are 110 patients with the operation of stereotaxis nervus nucleus damage -that are 9 spasticity kinds,15 tremble kinds and 86 spasticity-tremble kinds(20 spasticity-oriented and 66 tremble-oriented).Results:The score of 110 patients between before and after treatment is different,having statistical significance(P<0.01).The state of"open"is(52.5±6.8) and the state of"close"is(61.3±6.0) before operation while the state of"open"is(22.1±7.0) and the state of"close"is(23.7±7.2) days before operation.Conclusion:The operation of stereotaxis nervus nucleus damage can improve various dyskinesia for Parkinson disease patients.
Keywords:Stereotaxis:Nervus nuclei lesion  Parkinson disease  Dyskinesia
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