广西农村居民慢性肾脏病流行病学调查

目的:了解广西农村居民慢性肾脏病(CKD)流行情况及危险因素,为做好CKD防治工作提供有力依据。方法:采用分层多级随机抽样方法,对广西18～74岁农村居民进行CKD抽样调查。被调查者均接受问卷调查,检测尿白蛋白/肌酐比率、血尿(离心后尿沉渣显微镜检查)和肾脏B超,结果异常者3个月后进行复查。用国人校正的简化MDRD公式计算估计肾小球滤过率(eGFR)。同时调查了CKD的相关危险因素。结果:广西农村居民白蛋白尿患病率5.35%,血尿患病率0.97%,肾结石患病率10.73%,肾功能下降率4.08%,CKD患病率9.47%。农村居民CKD危险因素依次肾结石、高血压、糖尿病、年龄、高尿酸血症、慢性扁桃体炎和HBsAg阳性。居民CKD知晓率6.27%。结论:农村居民CKD发病率分别为9.47%,居民CKD知晓率,CKD相关危险因素肾结石、高血压、糖尿病、年龄、高尿酸血症、慢性扁桃体炎和HBsAg阳性。

Prevalence of chronic kidney disease in rural population in Guangxi

Objective To investigate the prevalence,awareness and risk factors of chronic kidney disease（CKD） among rural population in Guangxi,in order to provide information for prevention and treatment of CKD.Method A stratified multistage random sampling method was taken,18~74 years old residents in rural areas in Guangxi were survey.They were evaluated by questionnaire,urinary albumin/creatinine ratio,hematuria（microscopic examination of centrifuged urine sediment）,kidney B-mode ultrasound and abnormal results were reviewed 3 months later.The corrected glomerular filtration rate（eGFR） was estimated with corrected simplified MDRD formula.The risk factors associated with CKD was also investigated.Results The prevalence of albuminuria and hematuria was 5.35% and 0.97%,respectively.The prevalence of renal lithiasis in rural residents was 10.73%.The decreased of renal function was 4.08%.The prevalence of CKD was 9.47% in rural population.Based on logistic regression analysis,the risk factors for CKD in rural residents had followed by renal lithiasis,hypertension,diabetes,age,hyperuricemia,chronic tonsillitis,and positive HBsAg in rural.The awareness rate of CKD was 6.27%.Conclusion The prevalence of CKD in rural residents is 9.47%.The awareness rate of CKD in rural population is 6.27%.Independent risk factors of CKD includes renal lithiasis,hypertension,diabetes,age,hyperuricemia,chronic tonsillitis,and positive HBsAg.