| 芦丁铬（Ⅲ）配合物的合成、表征及其抗氧化活性研究 |
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| 引用本文： | 杨武群,吕华冲,蔡金艳,高奥,周鹏飞,王平,王健壮.芦丁铬（Ⅲ）配合物的合成、表征及其抗氧化活性研究[J].广东药学院学报,2012,28(5):493-496. |
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| 作者姓名： | 杨武群 吕华冲 蔡金艳 高奥 周鹏飞 王平 王健壮 |
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| 作者单位： | 广东药学院药科学院,广东广州,510006 |
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| 摘 要： | 目的合成芦丁-铬（Ⅲ）配合物后对其进行表征,并研究其抗氧化活性。方法以芦丁为先导化合物与微量元素铬合成芦丁-铬（Ⅲ）配合物。通过红外光谱、紫外可见光谱、元素分析、热重分析和原子吸收光谱对配合物进行表征。采用羟自由基（.OH）和超氧自由基（O2-.）模型测定了芦丁和芦丁-铬（Ⅲ）配合物的抗氧化活性。结果与结论确定芦丁-铬（Ⅲ）配合物中芦丁与铬的摩尔比为1∶1,推测分子式为CrCl2C27H32O18.7H2O。芦丁-铬（Ⅲ）配合物抗氧化作用比芦丁配体强。
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| 关 键 词： | 芦丁 铬 金属配合物 氧自由基 |
The synthesis, characterization and antioxidant properties of rutin-chromium (Ⅲ) complexes |
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| YANG Wu-qun
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Lü Hua-chong
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CAI Jin-yan
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GAO Ao
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ZHOU Peng-fei
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WANG Ping
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WANG Jian-zhuang.The synthesis, characterization and antioxidant properties of rutin-chromium (Ⅲ) complexes[J].Academic Journal of Guangdong College of Pharmacy,2012,28(5):493-496. |
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| Authors: | YANG Wu-qun Lü Hua-chong CAI Jin-yan GAO Ao ZHOU Peng-fei WANG Ping WANG Jian-zhuang |
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| Institution: | (Department of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,China) |
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| Abstract: | Objective To synthetize and characterize rutin-chromium（Ⅲ） complexes,and detect its antioxidation activities.Methods Rutin was taken as a lead compound,synthesized with trace element chromium and obtained rutin-chromium（Ⅲ） complexes.The complexes were confirmed by IR,UV-Vis,elemental analysis,thermo gravimetric analysis and atomic absorption spectrometric.Meanwhile,the antioxidation activities were investigated by hydroxyl radicals（·OH） and superoxide radicals（O-2·）.Results and Conclusion The molar ratio between rutin and chromium is 1∶1.The structural formula is inferred as CrCl2C27H32O18·7H2O.The antioxidation activities results demonstrate that rutin-chromium（Ⅲ） complexes is stronger than rutin on the antioxidation activities. |
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| Keywords: | rutin chromium metal complexes oxygen free radicals |
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