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四妙勇安汤不同提取部位抗炎作用的研究
引用本文:王光宁,李伟东,蔡宝昌.四妙勇安汤不同提取部位抗炎作用的研究[J].广东药学院学报,2009,25(4):389-391.
作者姓名:王光宁  李伟东  蔡宝昌
作者单位:1. 广东药学院中药学院,广东广州,510006
2. 南京中医药大学,江苏南京,210029
3. 江苏省中药炮制重点实验室,江苏南京,210029
摘    要:目的观察四妙勇安汤不同提取部位的抗炎作用。方法利用二甲苯致小鼠耳廓肿和大鼠琼脂性肉芽肿炎症模型,观察不同提取部位对炎症的影响。结果大孔树脂50%醇洗液部位对小鼠耳廓肿胀度有明显的抑制作用(P〈0.05);对大鼠琼脂性肉芽肿也有明显的抑制作用(P〈0.05,P〈0.01),且呈一定的量效关系。结论四妙勇安汤大孔树脂50%醇洗液部位具有显著的抗炎作用。

关 键 词:四妙勇安汤  提取部位  抗炎

Study of anti-inflammation actions of extractive fractions isolated from Simiaoyong' an decoction
WANG Guang-ning,LI Wei-dong,CAI Bao-chang.Study of anti-inflammation actions of extractive fractions isolated from Simiaoyong' an decoction[J].Academic Journal of Guangdong College of Pharmacy,2009,25(4):389-391.
Authors:WANG Guang-ning  LI Wei-dong  CAI Bao-chang
Institution:WANG Guang-ning1,LI Wei-dong2,CAI Bao-chang3(1.School of Traditional Chinese Medicine,Guangdong Pharmaceutical College,Guangzhou,Guangdong 510006,2.School of Traditional Chinese Medicine,Nanjing University of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,3.Jiangsu Provincial Key Laboratory of TCM Processing,China)
Abstract:Objective To investigate the anti-inflammation effects of extractive fractions isolated from Simiaoyong' an decoction. Methods The anti-inflammation actions of extractive fractions were examined in acute inflammation model in mice and chronic inflammation model in rats. Results Extraction fraction isolated with macroporous resin + 50% ethanol had obvious anti-inflammation action acute inflammation in mice ( P 〈 0.05 ) ; also had anti-inflammation action chronic inflammation in rats with obvious dosage-effect relationship (P 〈 0. 05 ,P 〈 0.01 ). Conclusion Extractive fraction isolated with macroporous resin + 50% ethanol had notable anti-inflammation actions.
Keywords:Simiaoyong ' an decoction  extractive fractions  anti-inflammation
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