| 壳聚糖在口服结肠定位给药系统中的应用 |
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| 引用本文： | 卢晓慧,周毅生.壳聚糖在口服结肠定位给药系统中的应用[J].广东药学院学报,2011,27(1):99-103. |
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| 作者姓名： | 卢晓慧 周毅生 |
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| 作者单位： | 广东药学院,中药学院,广东,广州,510006 |
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| 摘 要： | 壳聚糖是甲壳素脱乙酰化的产物，具有来源广泛、低毒、生物相容性好以及能够被生物降解等特性，是多种口服给药系统的良好载体，尤其在结肠定位系统中应用广泛。本文对壳聚糖理化性质、结构以及其在口服结肠定位给药系统中的应用作一综述。
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| 关 键 词： | 壳聚糖 结肠定位 给药系统 理化性质 |
The application of chitosan in the oral colon-specific drug delivery system |
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| LU Xiao-hui,ZHOU Yi-sheng.The application of chitosan in the oral colon-specific drug delivery system[J].Academic Journal of Guangdong College of Pharmacy,2011,27(1):99-103. |
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| Authors: | LU Xiao-hui ZHOU Yi-sheng |
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| Institution: | (Guangdong Pharmaceutical College,Guangzhou,Guangdong 510006,China) |
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| Abstract: | Chitosan is the outcome of chitin＇s deacetylation,which has a wide range of sources. Chitosan is a good carrier for many oral drug delivery systems, especially the oral colon-specific drug delivery system, for its low toxicity, good biocompatibility and biodegradability. The physiochemical property, structure and application in oral colon specific drug delivery system of chitosan are reviewed. |
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| Keywords: | chitosan colon-specific drug delivery system physicochemical property |
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