| 苦参化学成分研究 |
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| 引用本文： | 陈磊,刘怡,梁生旺.苦参化学成分研究[J].广东药学院学报,2011,27(5):471-473. |
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| 作者姓名： | 陈磊 刘怡 梁生旺 |
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| 作者单位： | 1. 广东药学院中药学院,广东广州,510006
2. 南方医科大学中药学院,广东广州,510515 |
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| 基金项目： | 广东高校优秀青年创新人才培养计划项目(LYM10095) |
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| 摘 要： | 目的 研究苦参化学成分.方法 采用柱层析色谱方法对苦参进行分离纯化,根据理化性质和波谱数据鉴定其结构.结果 从苦参中分离鉴定了8个化合物,分别为三叶豆紫檀苷(1)、高丽怀素(2)、4-羟基-3-甲氧基-8,9-二亚甲基二氧紫檀素(3)、异去氢淫羊藿素(4)、降脱水淫羊藿素(5)、7,4’-二羟基异黄酮(6)、7-甲氧基...
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| 关 键 词： | 苦参 化学成分 结构鉴定 |
Study on chemical constituents from Sophora flavescens |
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| CHEN Lei,LIU Yi,LIANG Sheng-wang.Study on chemical constituents from Sophora flavescens[J].Academic Journal of Guangdong College of Pharmacy,2011,27(5):471-473. |
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| Authors: | CHEN Lei LIU Yi LIANG Sheng-wang |
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| Institution: | CHEN Lei1,LIU Yi2,LIANG Sheng-wang1(1.School of Traditional Chinese Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China,2.School of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China) |
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| Abstract: | Objective To investigate chemical constituents from Sophora flavescens.Methods Compounds were isolated and purified by various chromatographic techniques.And their structures were elucidated with physicochemical properties and spectroscopic data.Results Eight chemical constituents were isolated and identified： trifolirhizin（1）,maackiain（2）,（-）-4-Hydroxy-3-methoxy-8,9-methyl-lenedioxypterocarpan（3）,isoanhydroicaritin（4）,noranhydroicaritin（5）,daidzein（6）,7-methoxy-4′-hydroxyisoflavone（7）,7-methoxy coumarin（8）,respectively.Conclusion Compound 7 and 8 are isolated from this plant for the first time,and 13C-NMR spectra data of compound 4 were supplemented. |
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| Keywords: | Sophora flavescens chemical constituents structural identification |
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