| 对《中国药典》（2005年版一部）薄层色谱法中部分含苯、甲苯展开剂的改进 |
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| 引用本文： | 陈蔼,梁洁莹,李书渊.对《中国药典》（2005年版一部）薄层色谱法中部分含苯、甲苯展开剂的改进[J].广东药学院学报,2009,25(4):360-362. |
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| 作者姓名： | 陈蔼 梁洁莹 李书渊 |
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| 作者单位： | 广东药学院中药学院,广东广州,510006 |
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| 摘 要： | 目的替换《中国药典》（2005年版一部）薄层鉴别中使用苯和甲苯的展开剂。方法用毒性较小的溶剂环己烷、正己烷、石油醚和三氯甲烷等取代苯或甲苯。结果可获得等同效果或效果更好的薄层色谱。结论建议《中国药典》逐步取消具有一定致癌性和强毒性的苯及甲苯。
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| 关 键 词： | 《中国药典》 薄层色谱法 展开剂 |
Modification of the developing agent in thin-layer chromatography |
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| CHEN Ai,LIANG Jie-ying,LI Shu-yuan.Modification of the developing agent in thin-layer chromatography[J].Academic Journal of Guangdong College of Pharmacy,2009,25(4):360-362. |
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| Authors: | CHEN Ai LIANG Jie-ying LI Shu-yuan |
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| Institution: | CHEN Ai,LIANG Jie-ying,LI Shu-yuan(Department of Traditional Chinese Medicine,Guangdong Pharmacutical College,Guangzhou,Guangdong 510006,China) |
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| Abstract: | Objective To replace the developing agents benzene and toluene in thin-layer chromatography in the Chinese Pharmacopoeia 2005 Volume I. Methods Less toxic solvents such as cyclohexane,n-hexane,petroleum ether and chloroform were compared with benzene and toluene. Results Cyclohexane,n-hexane,petroleum ether and chloroform had the same or better results in thin-layer chromatography. Conclusion Benzene and toluene could be replaced by other less toxic solvents in the pharmacopeia. |
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| Keywords: | drug control TLC developer agent |
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