瘀热相搏证的提出及对中医临床实践的指导作用

瘀热相搏证是在急性外感热病或内伤杂病病变发展的一定阶段,火热毒邪或兼夹痰湿壅于血分,搏血为瘀,致血热、血瘀两种病理因素互为搏结、相合为患而形成的一种特殊的证候类别。其病因为火热毒邪;病位深在营血、脉络;病理变化为瘀热搏结,脏腑受损;治疗大法为凉血化瘀。我们以“瘀热相搏”主证为基础,根据病证、病位、病理特点,分别针对流行性出血热急性肾功能衰竭的瘀热水结证、重症肝炎的瘀热发黄证、出血性疾病的瘀热血溢证、出血性中风的瘀热阻窍证及高脂血症的络热血瘀证等若干子证,进行了理论、临床、实验及新药开发等较为系统的研究,显示了中医以“证候”为中心的研究特色。

Guiding Significance of Postulation of Theory of Mixed Stasis- Heat Syndrome on TCM Clinical Practice

The mixed stasis-heat syndrome occurs at a certain stage of development of acute exogenous febrile diseases or internal miscellaneous diseases,when heat,toxin and phlegm-dampness accumulate in the blood system,causing the formation of blood heat and blood stasis,which combine to form a special syndrome.The syndrome is caused by heat and toxin and is located deeply in the ying system and collaterals,manifested by damage to the zang-fu organs,and therefore should be treated by cooling blood and removing blood stasis.The authors carried out theoretical,clinical and experimental studies systematically on the stasis heat and water retention syndrome of patients with epidemic hemorrhagic fever and acute renal failure,stasis heat and jaundice syndrome of serious hepatitis patients,stasis heat and blood extravasation syndrome of hemorrhagic disease patients,syndrome of stasis heat blocking the orifice of hemorrhagic apoplexy patients and excessive heat and blood stasis syndrome of patients with hyperlipemia patients,which shows the feature of considering "syndromes" as the core in TCM research.