|
|||||
|
|
| 35例绝经后乳腺癌新辅助内分泌治疗近期疗效临床分析 | |
| 引用本文： | 张苑珑,尤琪,孙晓光,杜梅,吴春风,孙宏华,刘杰.35例绝经后乳腺癌新辅助内分泌治疗近期疗效临床分析[J].中国伤残医学,2011,19(2):14-15. |
| 作者姓名： | 张苑珑 尤琪 孙晓光 杜梅 吴春风 孙宏华 刘杰 |
| 作者单位： | 1. 哈尔滨市红十字中心医院普外科,黑龙江,哈尔滨,150076 2. 哈尔滨医科大学附属第一临床医学院 3. 哈尔滨市妇幼保健院 |
| 摘 要： | 目的:探讨绝经后乳腺癌术前新辅助内分泌治疗的近期疗效。方法:35例老年乳腺癌患者术前服用芳香化酶抑制剂4～9个月后进行手术。结果:术前内分泌治疗,完全缓解2例(5.7%),部分缓解27例(77.1%),无变化3例(8.6%),进展3例(8.6%)。结论:绝经后、ER(+)乳腺癌病人采用来曲唑治疗有效、安全、可靠,为缩小手术切除术式创造条件,尤对年迈、体弱、和并其他严重疾病患者很好的治疗选择。 |
| 关 键 词： | 经后 乳腺癌 新辅助内分泌治疗 |
Short-term Observiation on Neoadjuvant Endocrine Therapy of Postmenopausal Breast Cancer in 35 patients |
|
| Institution: | ZHANG Yuan-long,YOU Qi,SUN Xiao-guang,et al. 1 Harbin Red Cross Centro Hospital,Heilongjiang Harbin(150076);2 The First Affilimed Hospital of Harbin Medical University,Heilongjang Harbin(150001); |
| Abstract: | Objective:To evaluate the short—term offects of neoadjuvant endocrin,therapy(NET)on postmenopausal breast cancer patients Methods:Thirty five case of postmenopausal breast cancer patients with stageⅡandⅢwere treated with letrozole for 4 months before operation.Results:Preoperative neoadjuvant endocrin,therapy,complete remission 2 patients(5.7%),partial remission 27 patients(77.1%)no change 3 patients(8.6%),progression 3patients(8.6%).Conclusion:NET with letrozole as a treatment option for postmenopausal patiems with receptor-positiv breast cancer might effective and safe,especially for elderly women who cannot tolerat the toxicities of chemotherapy or concomitant with some serious diseases who are no eligible for radical mastectomy. |
| Keywords: | Post-menopause Breastcancer Neoadjuvant endocrine therapy |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |