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幽门螺杆菌感染与冠心病的关系研究
引用本文:王岳屏,谌剑飞,严颂琴,田贺暖,井辉.幽门螺杆菌感染与冠心病的关系研究[J].疑难病杂志,2008,7(2):74-76.
作者姓名:王岳屏  谌剑飞  严颂琴  田贺暖  井辉
作者单位:1. 广东省珠海市第二人民医院心内科,519020
2. 广东省珠海市第二人民医院放免中心,519020
摘    要:目的探讨幽门螺杆菌(Hp)感染与冠心病发病的关系。方法以14C-尿素呼气试验对34例冠心病患者(冠心病组)进行Hp检测,并与35例健康体检者(健康对照组)进行对照,比较两者Hp阳性感染发生率和程度。结果冠心病组Hp阳性感染率(88.2%)显著高于健康对照组(51.2%)(P<0.01),感染程度(中重度)(46.7%)高于对照组(11.1%),差异也有统计学意义(P<0.01)。结论Hp感染与冠心病关系密切,其可能是冠心病的发病机制之一。

关 键 词:感染  幽门螺杆菌  冠心病  关系研究
文章编号:1671-6450(2008)02-0074-03
修稿时间:2007年10月11

Correlation between Helicobacter pylori infection and coronary he art disease
WANG Yue-ping,CHEN Jian-fei,YAN Song-qin,et al..Correlation between Helicobacter pylori infection and coronary he art disease[J].Journal of Difficult and Complicated Cases,2008,7(2):74-76.
Authors:WANG Yue-ping  CHEN Jian-fei  YAN Song-qin  
Institution:WANG Yue-ping,CHEN Jian-fei,YAN Song-qin,et al.Department of Cardiology,Zhuhai Second People's Hospital,Guangdong,Zhuhai 519020,China
Abstract:Objective To investigate the correlation between Helicobacter pylori(Hp)infection and coronary heart disease.Methods Hp was tested in 34 patients with coronary heart disease(CHD group)and 35 healthy subjects(control group)by 14 C-urea breath test(14C-UBT).The Hp infection rate and degree were compared between the two groups.Results The Hp infection rate(88.2%)in CHD group was significantly higher that(51.2%)of control group(P<0.01).Moreover,there was a significant difference in infection degree(middle and severe degree)between two groups(46.7% vs 11.1%,P<0.01).Conclusion Hp infection is closely related with coronary heart disease,which may be one of the pathogenesis mechanisms of coronary heart disease.
Keywords:Infection  Helicobacter pylori  Coronary heart disease  Correlation research
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