通心络胶囊联合依那普利治疗2型糖尿病肾病临床观察

目的　观察通心络联合依那普利治疗 2型糖尿病肾病的临床疗效。方法　选用 2型糖尿病肾病 94例随机分为治疗组、对照组 ,治疗组 ( 4 7例 )应用通心络胶囊联合依那普利治疗 ,疗程 4月 ;对照组 ( 4 7例 )仅用依那普利。结果　治疗组降低尿蛋白、改善肾功能作用明显优于对照组 (P <0 .0 5 ) ,且在降血压、改善血糖、调脂等方面的作用亦明显优于对照组 (P <0 .0 5 )。结论　治疗 2型糖尿病肾病患者应用通心络胶囊联合依那普利有较好的改善及保护肾功能 ,减少尿蛋白作用 ,且对 2型糖尿病患者血压、血糖、血脂均有良好的作用 ,值得临床使用

Therapeutic effect of Tongxinluo capsule combined with enalapril on type 2 diabetic nephropathy

Objective To investigate the therapeutic effect of Tongxinluo capsule combined with enalapril on type 2 diabetic nephropathy.Methods 94 patients with type 2 diabetic nephropathy were randomly divided into two groups. 47 patients in treatment group were treated with Tongxinluo capsule combined with enalapril;the other 47 patients in control group were treated with enalapril only,with a treatment course of four months for both groups.Results The effects of reducing proteinuria and improving renal function in treatment group were superior to those in control group (P<0.05); simultaneously in the effects of reducing blood pressure and improving blood glucose and blood lipid (P<0.05).Conclusion Tongxinluo capsule combined with enalapril is effective in treating type 2 diabetic nephropathy, which can protect renal function, reduce proteinuria, decrease blood pressure and improve blood glucose and blood lipid, thus which deserves clinical application.