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肾恶性孤立性纤维肿瘤1例并文献复习
引用本文:肖茂林,王德林,吴小侯,陈在贤,高飞,杨磊,翁红庆,蒋立.肾恶性孤立性纤维肿瘤1例并文献复习[J].重庆医学,2017,46(18).
作者姓名:肖茂林  王德林  吴小侯  陈在贤  高飞  杨磊  翁红庆  蒋立
作者单位:重庆医科大学附属第一医院泌尿外科 400016
基金项目:重庆市卫生与计划生育委员会适宜技术推广项目,重庆市科学技术委员会科技攻关项目
摘    要:目的 探讨肾恶性孤立性纤维肿瘤(SFT)的临床表现、影像学特点、诊断与鉴别诊断、治疗及预后.方法 回顾性分析1例罕见的肾恶性SFT患者的临床资料,结合相关文献分析该病的组织来源、病理学特征、鉴别诊断及治疗随访情况.结果 该例患者术前诊断为右肾透明细胞癌,行后腹腔镜根治性肾切除术,术后病理为右肾低度恶性SFT,免疫组织化学提示CD34、BCL-2、CD68、CD99、vimentin阳性表达,Ki-67 5%阳性表达及SMA局灶弱阳性.随访4个月,未见肿瘤复发或转移.结论 肾恶性SFT非常罕见,诊断与鉴别诊断依据术后病理学及免疫组织化学,主要治疗方式为根治性肾切除术,预后较好.

关 键 词:孤立性纤维肿瘤    间叶细胞肿瘤

Renal malignant solitary fibrous tumor: 1 case report and literature review
Xiao Maolin,Wang Delin,Wu Xiaohou,Chen Zaixian,Gao Fei,Yang Lei,Weng Hongqing,Jiang Li.Renal malignant solitary fibrous tumor: 1 case report and literature review[J].Chongqing Medical Journal,2017,46(18).
Authors:Xiao Maolin  Wang Delin  Wu Xiaohou  Chen Zaixian  Gao Fei  Yang Lei  Weng Hongqing  Jiang Li
Abstract:Objective To investigate the clinicalmanifestations,imaging features,diagnosis and differential diagnosis,treatment and prognosis of renal malignant solitary fibrous tumor(SFT).Methods The clinical data in 1 case of rare renal malignant SFT were retrospectively analyzed.Referring to related literatures,the histological origin,pathological features,differential diagnosis,treatment and follow-up of renal malignant SFT were analyzed.Results The patient was preoperatively diagnosed as right renal clear cell carcinoma.Postoperative pathological examination diagnosed as low grade malignant SFT of right kidney.And immunohistochemistry indicated CD34+,BCL-2 +,CD68+,CD99+,vimentin,Ki-67 5% +,SMA focal weakly positive.No recurrence or metastasis occurred after 4-month follow-up period.Conclusion Malignant SFT of the kidney is very rare,its diagnosis and differential diagnosis depend on postoperative pathological and immunohistochemical examination.Radical nephrectomy is the main option for malignant SFT of the kidney with good prognosis.
Keywords:solitary fibrous tumor  kidney  mesenchymal neoplasms
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