肺部真菌感染54例临床分析

目的 探讨肺部真菌感染的易患因素、临床特征、治疗和预后.方法 应用回顾性调查的方法对本院2005～2009年收治54例住院患者肺部真菌感染患者临床资料进行分析,诊断标准采用中华医学会<侵袭性肺部真菌感染的诊断标准与治疗原则>(草案).结果 95%(51/54)的病例患有基础疾病,其中以慢性阻塞性肺疾病(COPD)、系统性红斑狼疮、白血病和慢性肾病为多见;肿瘤性疾病也占有重要位置;原发性肺部真菌感染少见.肺部真菌感染的临床表现无特异性,X线表现以支气管肺炎多见(59.3%).病原菌主要以酵母菌属为主(79.5%),早期诊断困难.肺部真菌感染病死率较高.结论 多种疾病易继发肺部真菌感染,早期诊断较困难.其临床表现特异性少,发病呈上升趋势,病死率高,应引起临床高度重视.

54 cases of pulmonary fungal infection

Objective To find out the clinical features,therapeutic outcome,prognosis and the major predisposing diseases of pulmonary fungal infection(PFI).Methods 54 cases with PFI in local hospital during 2005 to 2009 were retrospectivelyanaly analyzed.Results Various predisposing diseases were found in 95% of total cases,among them,COPD,systemic lupus erythromatus(SLE),leukemia and chronic renal disease were main predisposing diseases.Primary pulmonaryfungal infection was rare.All the clinical manifestations of PFI...