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茶多酚对牙周主要致病菌的抗菌活性研究
引用本文:唐明,肖晓蓉,章锦才,朱珠.茶多酚对牙周主要致病菌的抗菌活性研究[J].重庆医学,2004,33(3):410-411.
作者姓名:唐明  肖晓蓉  章锦才  朱珠
作者单位:1. 重庆医科大学附属第一医院,400016
2. 四川大学华西口腔医学院,成都,610041
3. 广东省口腔医院,广州,510260
摘    要:目的测定茶多酚对口腔牙周分离的4种共66株优势病原菌的抗菌活性.方法采用琼脂稀释法测定茶多酚对实验细菌的最低抑菌浓度(MIC).结果茶多酚对牙龈卟啉单胞菌、中间普氏菌和具核梭杆菌的MIC50和MIC90分别为:125~250、125~250,125~250、125~250, 125~500、250~500mg/L,对变黑普氏菌的MIC为125 mg/L.结论茶多酚对牙周优势病原菌有抗菌作用.

关 键 词:茶多酚  牙周病原菌  抗菌活性  茶多酚  牙周  致病菌  抗菌作用  活性研究  in  vitro  pathogen  common  tea  polyphenol  变黑普氏菌  具核梭杆菌  中间普氏菌  牙龈卟啉单胞菌  结果  最低抑菌浓度  细菌  实验  琼脂稀释法  方法  抗菌活性
文章编号:1671-8348(2004)03-0410-02

The antibacterial activities of tea polyphenol against common periodontal pathogen in vitro
TANG Ming,XIAO Xiao rong,ZHANG Jin cai,et al..The antibacterial activities of tea polyphenol against common periodontal pathogen in vitro[J].Chongqing Medical Journal,2004,33(3):410-411.
Authors:TANG Ming  XIAO Xiao rong  ZHANG Jin cai  
Abstract:Objective To observe the antibacterial activities of tea polyphenol against 4 common periodontal bacteria in vitro. Methods The agar dilution method was used to detect the minimal inhibition concentration(MIC) of tea polyphenol against 66 stains of Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens and Fusobacterium nucleatum . Results All bacteria were inhibited by tea polyphenol. For P. gingivalis and P. intermedia, the MIC 50 and MIC 90 values were 125-250mg/L respectively; For P.nigrescens, the MIC value was 125mg/L;For F. nucleatum, the MIC 50 and MIC 90 values were 125-500mg/L and 250-500mg/L respectively. Conclusion All bacteria were susceptible to tea polyphenol. Tea polyphenol is significant for periodontal treatment.
Keywords:tea polyphenol  periodontal pathogen  antibacterial activity
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