米索前列醇预防产后出血52例分析

目的探讨米索前列醇在预防产后出血中的效果。方法回顾性分析该院2009年1月至2010年12月100例正常单胎足月的自然分娩患者,将其随机分为观察组52例和对照组48例,观察组产妇在胎儿娩出后口服米索前列醇片400μg或600μg,对照组在胎儿娩出后肌内注射缩宫素20U,分别测定两组产妇的出血量、第三产程时间、产后出血发生率和血压等指标。结果两组在第三产程时间、产后2h出血量、产后出血发生率等方面比较,差异有统计学意义(P<0.05)。结论米索前列醇口服给药促进子宫收缩作用强于肌内注射缩宫素,能有效缩短第三产程,减少产后出血。

Analysis of the effects of misoprostol on the prevention of postpartum hemorrhage in 52 cases

Objective To evaluate the effects of misoprostol on the prevention of postpartum hemorrhage.Methods 100 normal term single birth parturients that spontaneous labored were randomly orally given misoprostol 400 or 600 μg(experimental group),or intramuscularly given oxytocin 20 U(control group) after fetal disengagement.The hemorrhage volume,blood pressure,the time of third stage of labo and the rate of hemorrhage were examined.Results There was a remarkable difference in the time of third stage of labor,hemorrhage volume and the rate of hemorrhage between the experiment group and the control group(P<0.05).Conclusion Misoprostol that orally given can effectively promote uterine contraction,decrease postpartum hemorrhage volume,reduce the third stage of labor,and is better than oxytocin.