| ^13CNMR在黄酮甙类化合物结构鉴定中的应用 |
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| 引用本文： | 刘勤.^13CNMR在黄酮甙类化合物结构鉴定中的应用[J].中国医学科学院学报,1990,12(5):359-364. |
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| 作者姓名： | 刘勤 |
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| 作者单位： | 中国医学科学院药用植物资源开发研究所 北京 |
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| 摘 要： | 用核磁共振碳谱(~(13)CNMR)分析和鉴定豆科甘草属植物黄甘草(Glycyrrhiza eurycarpaP.C.Li)中13种黄酮甙类化合物的结构,结果表明它们分属于5种不同骨架类型的黄酮类化合物:异黄酮、双氢黄酮、查尔酮、黄酮和紫檀烷。通过对C-环碳(C_2～C_4)化学位移值的分析比较,证明藉碳谱数据可决定甙元的骨架类型和C_5位是否存在羟基;结合其他光谱数据,可确定糖基的种类及构型和甙键类型。此外,碳谱分析也可提供黄酮母核取代基位置、甙化位置和糖基之间连接方式的信息。
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| 关 键 词： | 碳谱 黄甘草 黄酮类 异黄酮甙 双氢黄酮甙 查尔酮甙 黄酮甙 紫檀烷甙 |
Application of ~(13)CNMR to Structural Identification of the Flavonoid Glycosides |
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| Liu Qin and Liu Yonglong.Application of ~(13)CNMR to Structural Identification of the Flavonoid Glycosides[J].Acta Academiae Medicinae Sinicae,1990,12(5):359-364. |
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| Authors: | Liu Qin and Liu Yonglong |
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| Institution: | Institute of Medicinal Plant Development, Beijing. |
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| Abstract: | ~(13)CNM R has become an important method for the structural determination of organic natural products. It is especially useful for identifying the structure of glycosides, This paper deals with the application of ~(13)CNMR to the identification of the flavonoid glycosides isolated from the roots of Glycyrrhiza eurycarpa P. C. Li. The discrimination of chemical shifts of C-2, C-3 and C-4 (carbonyl) signals for different types of flavonoids, such as isoflavones, flavanones, chalcones, flavones and pterocarpans, is discussed. The application of ~(13)CNMR in the determination of structure and configuration of sugar moieties, for determination of glycosidic linkage, and for confirmation of the position of glycosidation and linkage between two sugar moieties are also discussed briefly. |
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| Keywords: | (13)~CNMR Glycyrrhiza eurycarpa flavonoid glycosides isoflavones flavanones chalcones flavones pterocarpans |
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