16层螺旋CT在下肢动脉闭塞性疾病中的应用

目的 探讨16层螺旋CT在诊断下肢动脉闭塞性疾病中的临床应用价值。方法 对30例临床可疑的外周动脉闭塞性疾病患者行下肢动脉16层螺旋CT血管造影（CTA）,所有患者于CTA检查前或后2周内行数字减影血管造影（DSA）。CTA重建采用最大密度投影（MIP）、容积再现技术（VRT）及曲面重建（CPR）。以DSA为金标准,评价CTA诊断的准确性。结果 CTA诊断下肢动脉≥50％狭窄的敏感性为94．3％（115／122）,特异性为98．4％（548／557）,准确率97．6％（663／679）,阳性预测值为92．7％（115／124）,阴性预测值为98．7％（548／555）。结论 16层螺旋CT诊断下肢动脉闭塞性疾病有较高的敏感性、特异性和准确性,可部分性替代DSA检查。

Application of 16-slice spiral CT in lower extremity arterial occlusive diseases

OBJECTIVE: To determine the diagnostic accuracy of 16-slice spiral CT in assessing the lower extremity arterial occlusive diseases. METHODS: Thirty patients with suspected peripheral arterial occlusive diseases underwent 16-slice spiral CT angiography (CTA) of lower extremity arteries. All these patients also underwent digital subtraction angiography (DSA) two weeks before or after CTA. CT angiograms were produced using maximal intensity projection, volume rendering technique, and curved planar reconstruction. Using DSA as the standard reference, the diagnostic accuracy of CTA was determined. RESULTS: When detecting segments with > or = 50% stenosis, the sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of CTA were 94.3% (115/122), 98.4% (548/557), 97.6% (663/679), 92.7% (115/124), and 98.7% (548/555), respectively. CONCLUSION: 16-slice spiral CT has high sensitivity, specificity, and accuracy in detecting lower extremity arterial occlusive diseases and may partially substitute DSA examinations.