| P物质、血管活性肠肽和神经肽Y在大鼠颌下腺分布与共存的免疫组织化学研究 |
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| 引用本文： | 贾雪梅,贾友苏,王惠珠,齐威琴,侯思伟,潘朝宠.P物质、血管活性肠肽和神经肽Y在大鼠颌下腺分布与共存的免疫组织化学研究[J].中国医学科学院学报,1997,19(2):107-109. |
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| 作者姓名： | 贾雪梅 贾友苏 王惠珠 齐威琴 侯思伟 潘朝宠 |
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| 作者单位： | 安徽医科大学!合肥，230032，安徽医科大学!合肥，230032，安徽医科大学!合肥，230032，安徽医科大学!合肥，230032，安徽中医学院针灸经络研究所，安徽中医学院针灸经络研究所 |
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| 摘 要： | 采用免疫组织化学ABC方法观察了P物质（SP）、血管活性肠肽（VIP）和神经肽Y（NPY）等神经肽在大鼠颌下腺内的分布和共存关系结果显示，颌下腺内有SP能、VIP能和NPY能神经支配，纤维呈串珠状或线状，主要走行于腺泡、导管和血管周围。颌下腺内副交感神经节细胞均呈SP、VIP和NPY免疫组化反应阳性。提示这些神经肽共存于神经节细胞内，可能参与调节颌下腺复杂的分泌活动和有效的血液供应。
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| 关 键 词： | P物质 血管活性肠肽 神经肽Y 颌下腺 免疫组织化学 大鼠 |
Immunohistochemical Study on the Distribution and Coexistence of SP, VIP and NPY in the Rat Submandibular Gland |
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| Jia Xuemei, Jia Yousu, Wang Huizhu, Qi Weiqin,Hou Siwei, et al.Immunohistochemical Study on the Distribution and Coexistence of SP, VIP and NPY in the Rat Submandibular Gland[J].Acta Academiae Medicinae Sinicae,1997,19(2):107-109. |
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| Authors: | Jia Xuemei Jia Yousu Wang Huizhu Qi Weiqin Hou Siwei |
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| Institution: | Anhui Medical University, Hefei. |
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| Abstract: | The distribution and coexistence of SP, VIP and NPY in the submandibur gland of rat have been studied with immunohistochemical ABC methods. The results indicated that SP, VIP and NPY-IR nerve fibers were presented as varicose and linear profiles, which mainly travelled around acini, duct and blood vessels. The ganglion cells in submandibular gland showed SP, VIP and NPY-IR all positive immunocytochemically. The findings indicated that the neuropeptides were coexisted in the same neuron body and might play the role of regulation of the secretary activity and effective blood supply. |
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| Keywords: | substance P vasoactive intestinal polypeptide neuropeptide Y submandibular gland immunohistochemistry rat |
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