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131I治疗Graves甲亢近期疗效评价
引用本文:武海明,谭天秩,匡安仁,管昌田.131I治疗Graves甲亢近期疗效评价[J].山西医科大学学报,2002,33(6):532-533.
作者姓名:武海明  谭天秩  匡安仁  管昌田
作者单位:四川大学华西医院核医学科,成都,610041
摘    要:目的:评价放射性碘^131I)治疗毒性弥漫性甲状腺肿(Graves病)的近期临床疗效。方法:对接受^131I治疗的278例Graves甲亢患者随访1年。所有病人于治疗后3、6、12个月复诊。治疗结果包括治愈(包括治疗后甲状腺功能恢复正常与发生甲低)和未愈(甲亢)。结果:治疗后3个月,有179例(64.3%)患者甲状腺功能恢复正常,35例(12.6%)发生甲低,64例(23.1%)仍处于甲亢,治愈率为76.9%。治疗后半年与一年的治愈率相似(84.6%vs88.8%),均显著性高于3个月,分别有193例(69.5%)和196例(70.5%)甲状腺功能恢复正常,42例(15.1%)和51例(18.3%)发生甲低。结论:^131I能迅速治愈甲亢,疗效显著,简便安全,是成人Graves甲亢的首选 治疗方法。

关 键 词:疗效  格雷夫斯病  甲状腺功能亢进  碘放射性同位素  放射疗法
文章编号:1007-6611(2002)06-0532-02

Short-term effects of radioiodine treatment on Graves' hyperthyroidism
WU Hai-ming,TAN Tian-zhi,KUANG An-ren,et al.Short-term effects of radioiodine treatment on Graves'''' hyperthyroidism[J].Journal of Shanxi Medical University,2002,33(6):532-533.
Authors:WU Hai-ming  TAN Tian-zhi  KUANG An-ren  
Abstract:Objective To evaluate the short-term efficacy of radioiodine ( 131 I)therapy in Graves' hyperthyroidism. Methods A total of 278 patients with Graves' disease were treated with a single dose of 131 I. All patients were followed up for one year and reexamined at 3,6 and 12 months after 131 I treatment.Results Of the 278 patients, 76.9%(214/278)were cured after 3 months withradioiodine.While after 6 and 12 months,the cure rates were similar(84.6% vs 88.8%),and both were higher than that after 3 months. Conclusion A single dose of 131 I is highly effective for curing Graves' hyperthyroidism,so it is used as first line therapy for adult Graves's hyperthyroidism.
Keywords:Graves' disease  hyperthyroidism  iodine radioisotopes  radiotherapy
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