| 氯胺酮致泌尿系统损害35例临床分析 |
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| 引用本文： | 黄志扬,林俊雄,吴文峰,沈倚天.氯胺酮致泌尿系统损害35例临床分析[J].山西医科大学学报,2011,42(4):346-348. |
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| 作者姓名： | 黄志扬 林俊雄 吴文峰 沈倚天 |
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| 作者单位： | 福建医科大学附属泉州市第一医院泌尿外科,泉州,362000 |
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| 摘 要： | 目的探讨氯胺酮(K粉)引发泌尿系损害的诊治方法及可能机制。方法滥用K粉患者35例,年龄18-35岁,吸食K粉1-5年,均因严重的下尿路症状就诊,尿培养阴性,尿找结核菌阴性,尿红细胞形态正常或畸形,5例出现肾功能不全,IVP和CT检查提示10例出现双侧集合系统扩张和输尿管上段或全长扩张,其中膀胱挛缩2例并膀胱输尿管反流。结果患者停止或减少滥用K粉并药物治疗,30例血尿消失,20例尿频、下尿路症状缓解或消失,2例膀胱挛缩经保守治疗后,膀胱容量恢复正常。结论 K粉致沁尿系损害是一种以下尿路刺激症状为主要表现的全尿路可逆性炎症表现,停止使用K粉及对症处理可取得满意的效果。膀胱挛缩患者采用保守治疗,也能取得较好的效果。
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| 关 键 词： | 氯胺酮 药物滥用 泌尿系损害 |
Clinical analysis of ketamine-associated urinary tract dysfunction:a report of 35 cases |
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| HUANG Zhi-yang,LING Jun-xiong,WU Wen-feng,SHEN Yi-tian.Clinical analysis of ketamine-associated urinary tract dysfunction:a report of 35 cases[J].Journal of Shanxi Medical University,2011,42(4):346-348. |
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| Authors: | HUANG Zhi-yang LING Jun-xiong WU Wen-feng SHEN Yi-tian |
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| Institution: | HUANG Zhi-yang,LING Jun-xiong,WU Wen-feng,SHEN Yi-tian(Dept of Urology,Quanzhou First Hospital Affiliated of Fujian Medical University,Quanzhou 362000,China) |
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| Abstract: | Objective To explore the diagnosis and treatment of the ketamine-associated urinary system dysfunction and its possible mechanism.Methods A total of 35 ketamine abusers aged 18-35 years were collected.All of them had abused ketamine for 1-5 years,and presented with severe lower urinary tract symptoms.Urinalysis showed no bacterial pyuria and were negative for tuberculosis.The appearance of erythrocyte in urine was normal or abnormal.Five patients had renal dysfunction.Intravenous pyelography(IVP) and CT exa... |
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| Keywords: | ketamine drug abuse urinary system dysfunction |
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