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生精汤对雄激素致无排卵模型大鼠卵巢功能及形态学的影响
引用本文:周璐,章巧萍,徐孝平,陈京,徐小玉.生精汤对雄激素致无排卵模型大鼠卵巢功能及形态学的影响[J].浙江中医药大学学报,2006,30(6):621-622.
作者姓名:周璐  章巧萍  徐孝平  陈京  徐小玉
作者单位:浙江中医药大学,杭州,310053
摘    要:目的]观察补肾活血方药生精汤对雄激素致无排卵模型大鼠的作用及其对作用机制进行初步探讨。方法]幼年雌性SD大鼠注射外源雄激素制造不排卵模型,运用中医中药治疗并观察治疗前后动物动情周期、血清性激素水平以及卵巢病理形态组织学的变化。结果]本方能恢复正常动情周期、改善血清激素水平;缩小卵巢扩张囊泡、增加黄体数量。结论]生精汤具有改善模型大鼠多囊卵巢征象、促排卵、恢复卵巢功能的作用。

关 键 词:多囊卵巢综合征  生精汤  大鼠  克罗米芬胶虫
文章编号:1005-5509(2006)06-0621-02
收稿时间:2006-08-11
修稿时间:2006-08-11

Effect of the Sheng Jing Tang on the Ovarian Funtion and Morphology of Female Rat Anovulatory Due to Testosterone
Zhou Lu, Zhang Qiaoping, Xu Xiaoping, et al.Effect of the Sheng Jing Tang on the Ovarian Funtion and Morphology of Female Rat Anovulatory Due to Testosterone[J].Journal of Zhejiang University of Traditional Chinese Medicine,2006,30(6):621-622.
Authors:Zhou Lu  Zhang Qiaoping  Xu Xiaoping  
Abstract:Objective] To investigate the effects of the Sheng Jing Tang, one of tonyfing kidney and promoting blood circulation recipes,on female rats anovulatory due to testosterone and to study the mechanism of action of the recipe. Methods] The rat models of anovulatory disease were established by injecting the immature female SD rat with testosterone and treated with TCM and herbs to observe estrous cycle level of sex hormone of blood and the change of pathological histology of ovary. Results] Sheng Jing Tang could improve the level of sex hormone, contract the expanded oxarian vesicles obviously and increase the quantity of luteum. Conclusions] Sheng Jing Tang had the effect of improving the syndromes of Polycystic Ovary, inducing ovulation and recovering the function of ovary.
Keywords:polycystic ovary syndrome (PCOS)  Sheng Jing Tang  animal model of PCOS  
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