运脾固表法防治小儿反复呼吸道感染的肠道微生态机制研究

目的]探讨运脾固表法对反复呼吸道感染儿的肠道微生态的影响。方法]选择1～12岁肺脾气虚型反复呼吸道感染患儿60例，随机分为治疗组30例，对照组30例，治疗组口服运脾固表的中药复感宁方，对照组口服培菲康散（双歧三联活菌），疗程12周，比较两组治疗后双歧杆菌和肠杆菌菌群变化及B／E值，并与正常组对照。结果]治疗后治疗组粪便标本中的双歧杆菌含量高于对照组（P〈0．05），B／E值也高于对照组（P〈0．05），而肠杆菌含量两组比较差异无显著意义（P〉0．05）。治疗后两组粪便标本中的双歧杆菌含量及B／E值都仍然低于正常组（P〈0．05），治疗组肠杆菌与正常组比较差异无显著意义（P〉0．05），对照组则仍高于正常组（P〈0．05）。结论]运脾固表法能提高反复呼吸道感染儿肠道中双歧杆菌的数量及B／E值，降低肠杆菌含量，改善肠道微生态结构。

Mechanism Study on Intestinal Microecology of Children Recurrent Respiratory Tract Infection Prevented and Treated with Method of Activating Spleen to Solidify Superficial

Objective] To explore the effect of the method of activating spleen to solidify superficial on intestinal microecology of children recurrent respiratory tract infection.Method] Select 60 cases aged 1~12 of Qi deficiency type of lung and spleen in recurrent respiratory tract infection,randomly divide them into treatment group 30 cases and control 30;the treatment one takes TCM Fugangning formula orally for activating spleen to solidify superficial;the other takes orally BIFICO,for 12 w;compare their Bifido...