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兴奋性突触后电位沿树突传输的定量分析方法
引用本文:刘学宗,张英才.兴奋性突触后电位沿树突传输的定量分析方法[J].首都医学院学报,1992,13(3):181-185.
作者姓名:刘学宗  张英才
作者单位:首都医学院数学教研室,首都医学院数学教研室,首都医学院计算机教研室,首都医学院生理学教研室,首都医学院生理学教研室
摘    要:提出一种以电缆方程为物理模型,根据刺激脊髓在鲫鱼Mauthner细胞腹侧树突上测量出的EPSP实验数据,对膜的特性和突触的分布特性进行定量分析的方法。运用到一组典型实验数据上,得出空间常数约412 μm,时间常数约1.8 ms,同时得出,在树突远端兴奋性突触密度最大(时间平均兴奋性作用强度可达8.4 mV,瞬间兴奋性作用强度可达44 mV,而中间部位的密度为树突远端突触密度的44%,靠近胞体处的密度为11%。

关 键 词:Mauthner细胞  兴奋性突触后电位  电缆方程
收稿时间:1991-05-30

A Quantitative Procedure for Analyzing EPSP Transmission along the Ventral Dendrite of the Teleost Mauthner Cell
Liu Xuezong,Tong Longzheng,Guo Decheng,Chang Yincai,Zhang Shuhua Capital Institute of Medicine.A Quantitative Procedure for Analyzing EPSP Transmission along the Ventral Dendrite of the Teleost Mauthner Cell[J].Journal of Capital University of Medical Sciences,1992,13(3):181-185.
Authors:Liu Xuezong  Tong Longzheng  Guo Decheng  Chang Yincai  Zhang Shuhua Capital Institute of Medicine
Institution:Capital Institute of Medicine
Abstract:In this paper, a procedure was proposed, based on the linear cable equation and experi-mental observations, for analyzing electric signal transmission due to electrotonic propagation along a central neuron. The procedure was used to predict the characters of the membrane and the synaptic density along the ventral dendrite of the teleost Mauthner cell. For a typical group of experimental data, it was given that the membrane space constant is about 412μm, the time constant about 1.8 ms, and the synaptic density at 300 and 100μm. was 44% and 11% of that at 600 μm, respectively.
Keywords:Mauthner cell  EPSP  cable equation  
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