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异位妊娠发病因素十年变迁
引用本文:汤丽荣,郑萍.异位妊娠发病因素十年变迁[J].首都医学院学报,2010,31(6):817-820.
作者姓名:汤丽荣  郑萍
作者单位:首都医科大学附属北京妇产医院妇科 
摘    要:目的探讨不同时期异位妊娠发病因素的差异,以探索切实可行的干预措施。方法对首都医科大学附属北京妇产医院1997年10月~1998年9月期间(前期组)186例和2007年10月~2008年9月期间(后期组)382例异位妊娠患者发病的相关因素进行回顾性分析,包括年龄、婚姻状况、孕产史、职业分布、既往病史和治疗情况等。结果 2组患者平均年龄差异无统计学意义,后期组20岁以下构成比由10年前的1.1%上升至4.5%(P=0.006);未婚女性由1997年的21.5%上升至2007年的41.4%(P=0.000);未育女性由1997年的45.7%上升至2007年的66.8%(P=0.000);2组间孕、产次差异无统计学意义,但后期组流(引)产次数明显高于前期组(P=0.030);职业分布:工人、农民的构成比明显下降,干部、职员和学生、其他职业的构成比逐年上升(P=0.000);前期组患者宫内节育器病史明显多于后期组(P=0.000),而生殖道感染史和其他腹部手术史明显少于后期组(P=0.002,P=0.044)。后期组中阴道灌洗史、宫颈治疗史及吸烟史均较前期组明显增高(P=0.000,P=0.009,P=0.002)。结论 10年来异位妊娠发病相关因素发生了变化,应采取相应的措施,以降低异位妊娠的发生。

关 键 词:不同时期  异位妊娠  发病因素
收稿时间:2010-03-05

Changes in the Risk Factors of Ectopic Pregnancy in Ten Years
TANG Li-rong,ZHENG Ping.Changes in the Risk Factors of Ectopic Pregnancy in Ten Years[J].Journal of Capital University of Medical Sciences,2010,31(6):817-820.
Authors:TANG Li-rong  ZHENG Ping
Institution:Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Abstract:Objective To identify the changes of the risk factors of ectopic pregnancy(EP) in different periods and explore the effective interventions.Methods A retrospective study was conducted on 568 cases in Beijing Obstetrics and Gynecology Hospital,Capital Medical University which consists of two groups:the early group with 186 cases from Oct.1st 1997 to Sep.30th 1998;while the later group with 382 cases from Oct.1st 2007 to Sep.30th 2008.The risk factors such as age,marriage,pregnancy history,profession,previous medical history and treatment were compared.Results There was no significant difference in average age between the two groups.The rate of women whose age was less than 20 years in the early group was much lower than that in the later group(1.1% vs 4.5%,P=0.006).The rate of unmarried women increased from 21.5% in 1997 to 41.4% in 2007(P=0.000) while the rate of nulliparous women increased from 45.7% in 1997 to 66.8% in 2007(P=0.000).There was no significant difference in pregnancy time and parity between the two groups(P=0.030).The abortion time in the later group was much higher than that in early group.The constituent ratio of worker and farmer apparently decreased while the constituent ratio of cadres,staff and student and other occupation increased by years(P=0.000).The patients with the history of intrauterine device(IUD) in early group was more than that in later group(P=0.000_ and patients with the history of reproductive tract infections(RTIs) and other abdominal surgery were lower than those in the later group(P=0.002,P=0.044).The rate of the history of vaginal lavage,cervical treatment and smoking in the later group were much higher than those in the early group(P=0.000,P=0.009,P=0.002).Conclusion Risk factors for EP altered in the past decade and efficient interventions should be applied accordingly to reduce the EP.
Keywords:different period  ectopic pregnancy  risk factor
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