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小剂量重组组织型纤维溶酶原激活剂治疗急性心肌梗死的疗效观察
引用本文:丁顺晶,李燕.小剂量重组组织型纤维溶酶原激活剂治疗急性心肌梗死的疗效观察[J].首都医学院学报,2010,31(2):280-281.
作者姓名:丁顺晶  李燕
作者单位:丁顺晶(首都医科大学附属北京天坛医院心血管内科);李燕(河北医科大学附属唐山工人医院心内科) 
摘    要:目的观察重组组织型纤维蛋白激活剂栓体舒(recombinant tissue plasminogen activator,rTPA)在急性心肌梗死治疗中的临床疗效和不良反应。方法小剂量重组组织型纤维蛋白溶酶激活剂(栓体舒)50mg于90min内静脉注入,治疗急性心肌梗死患者72例,观察血管再通的临床指标、不良反应及病死率。结果梗死相关血管再灌注率75%,6周病死率4.17%,出血发生率14.17%。结论小剂量栓舒静脉溶栓治疗急性心肌梗死较安全有效。

关 键 词:急性心肌梗死  重组组织型纤维蛋白溶酶原激活剂  溶栓治疗

Therapeutic Effect of Low-dose Recombinant Tissue-type Plasminogen Activator on Acute Myocardial Infarction
DING Shun-jing,LI Yan.Therapeutic Effect of Low-dose Recombinant Tissue-type Plasminogen Activator on Acute Myocardial Infarction[J].Journal of Capital University of Medical Sciences,2010,31(2):280-281.
Authors:DING Shun-jing  LI Yan
Institution:DING Shun-jing1,LI Yan2(1.Department of Cardiovascular Internal Medicine,Beijing Tiantan Hospital,Capital Medical University,2.Department of Cardiovascular,Tangshan Worker\'s Hospital,Hebei Medical University)
Abstract:Objective To evaluate the therapeutic effect of recombinant tissue-type plasminogen activator(rTPA) on acute myocardial infarction.Methods 72 cases with acute myocardial infarction were treated by low-dose rTPA(50 mg) through 90 min vein injection,the clinic values of blood vessels recanalization,side effects and mortality were observed.Results Reperfusion rate of infarct related vessels was 75%,six-week mortality was 4.17%,bleeding rate was 14.17%.Conclusion It is safe and efficient of low-dose rTPA on acu...
Keywords:acute myocardial infarction  recombinant tissue plasminogen activator  thrombolytic therapy  
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