| 富氧水耐缺氧和抗疲劳作用 |
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| 引用本文： | 毕晓郁,齐娜,殷召雪,吴金华,高丽芳,曹丽歌,吴涛,胡子净,苏忆兰,陈振良.富氧水耐缺氧和抗疲劳作用[J].首都医学院学报,2008,29(4):467-470. |
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| 作者姓名： | 毕晓郁 齐娜 殷召雪 吴金华 高丽芳 曹丽歌 吴涛 胡子净 苏忆兰 陈振良 |
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| 作者单位： | [1]首都医科大学食品药品安全评价中心 [2]北京华意兴新技术开发研究所 |
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| 基金项目： | 北京市优秀人才培养基金 |
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| 摘 要： | 目的研究富氧水对小鼠的耐缺氧和抗疲劳作用。方法采用灌胃法给予小鼠不同剂量的富氧水,分别测定小鼠的常压耐缺氧时间、急性脑缺血性缺氧存活时间、亚硝酸钠中毒存活时间、负重游泳时间及小鼠游泳后血清尿素氮、血乳酸、肝糖原的含量。结果富氧水低剂量组(2.4mg/kg)小鼠常压耐缺氧生存时间较对照组显著延长(P<0.05);肝糖原储备量增加(P<0.05);血乳酸上升速度减慢(P<0.05);血乳酸曲线下面积降低(P<0.05)。与对照组比较,富氧水低剂量组急性脑缺血性缺氧生存时间、亚硝酸钠中毒存活时间和负重游泳时间差异无统计学意义,但有延长的趋势;小鼠运动后血清尿素氮含量也有降低的趋势。结论富氧水具有一定耐缺氧和抗疲劳作用。
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| 关 键 词： | 富氧水 耐缺氧 抗疲劳 小鼠 |
| 收稿时间： | 2007-09-18 |
Studies on Enhancing Anoxia Endurance and Anti-fatigue Function of Oxygenated Water |
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| Bi Xiaoyu,Qi Na,Yin Zhaoxue,Wu Jinhua,Gao Lifang,Cao Lige,Wu Tao,Hu Zijing,Su Yilan,Chen Zhenliang.Studies on Enhancing Anoxia Endurance and Anti-fatigue Function of Oxygenated Water[J].Journal of Capital University of Medical Sciences,2008,29(4):467-470. |
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| Authors: | Bi Xiaoyu Qi Na Yin Zhaoxue Wu Jinhua Gao Lifang Cao Lige Wu Tao Hu Zijing Su Yilan Chen Zhenliang |
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| Institution: | 1.Center of Food and Drug Safety Assessment;Capital Medical University;2.Beijing Huayixing Technology Development Academy |
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| Abstract: | Objective To investigate the effect of oxygenated water on anoxia endurance and anti-fatigue function in mice.Methods Mice were orally administered different doses of oxygenated water,survival time under anoxia,sodium nitrite poisoning or acute cerebral ischemia,loaded swimming time,serum urea nitrogen,plasma lactic acid content,and hepatic glycogen were determined.Results It was found that oxygenated water(2.4 mg/kg) could protract the anoxia survival time of mice under normal pressure(P<0.05).It could als... |
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| Keywords: | oxygynated water anoxia anti-fatigue mouse |
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