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血浆糖基与代谢综合征血糖组分关联性研究
引用本文:血浆糖基与代谢综合征血糖组分关联性研究.血浆糖基与代谢综合征血糖组分关联性研究[J].首都医学院学报,2015,36(4):614-617.
作者姓名:血浆糖基与代谢综合征血糖组分关联性研究
作者单位:1. 首都医科大学公共卫生学院流行病与卫生统计学系, 北京 100069; 2. 临床流行病学北京市重点实验室, 北京 100069; 3. 糖尿病防治研究北京市重点实验室, 北京 100005; 4. 首都医科大学附属北京同仁医院内分泌科, 北京 100730; 5. 首都医科大学附属北京同仁医院眼科, 北京 100730
基金项目:国家自然科学基金项目(81373099,81370083)。
摘    要:目的 探讨血浆糖基与代谢综合征血糖组分的关联性。方法 将患者按有无代谢综合征血糖组分异常划分为2组(≥5.6 mmol/L为异常),采用秩和检验比较两组糖基差异性;将差异有统计学意义的糖基位点代入Logistic回归探讨代谢综合征血糖组分的影响因素。结果 Logistic回归结果显示:GP5、GP11和A2三个糖基位点对代谢综合征血糖组分的影响具有统计学意义(P<0.05)。结论 GP5、GP11和A2三个糖基位点是代谢综合征血糖组分异常的影响因素。

关 键 词:糖基  预测模型  代谢综合征  血糖组分  
收稿时间:2015-02-15

Association between blood glycans and glucose of metabolic syndrome
Cao Kai,Wang Youxin,Liu Xiangtong,Tao Lixin,Guo Jin,Song Manshu,Yu Xinwei,Yang Jinkui,Wang Wei,Guo Xiuhua,Yang Guangran,Wei Wenbin.Association between blood glycans and glucose of metabolic syndrome[J].Journal of Capital University of Medical Sciences,2015,36(4):614-617.
Authors:Cao Kai  Wang Youxin  Liu Xiangtong  Tao Lixin  Guo Jin  Song Manshu  Yu Xinwei  Yang Jinkui  Wang Wei  Guo Xiuhua  Yang Guangran  Wei Wenbin
Institution:1. Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China; 2. Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing 100069, China; 3. Beijng Key Laboratory of Diabetes Research and Care, Beijing 100005, China; 4. Endocrinology Department, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; 5. Eye Department, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
Abstract:Objective To explore the association between blood glycans and glucose of metabolic syndrome. Methods Subjects are split into two groups according to glucose level(below 5.6 mmol/L is defined as normal). Wilcoxon rank sum test is applied to make comparison of glycan level between two groups and Logistic regression is applied to make sure the impact factors of blood glucose. Results GP5, GP11 and A2 are statistically significant with P value under 0.01. Conclusion GP5, GP11 and A2 are the impact factors of blood glucose.
Keywords:glycans  predictive model  metabolic syndrome  blood glucose  
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