冠心病危险因素聚集与冠脉病变的相关分析

目的：探讨对冠心病的危险因素聚集与冠状动脉病变的关系。方法：对已行冠状动脉造影最少有一支血管狭窄≥50％的病人进行冠心病危险因素的调查，并与冠脉造影所得结果进行相关分析。结果：冠心病危险因素评分与冠脉病变的综合评分呈正相关；冠心病危险因素的数量与冠脉病变综合评分呈正相关；单个危险因素危险程度依次为血压、吸烟、血糖、活动量、脾气性格、血脂、家族史、年龄性别、体重指数、尿酸、胆红素和职业：危险因素的量和程度的聚集可致冠脉病变程度和范围加重。结论：冠心病的危险因素及其在个体的聚集对冠心病的发生发展以及冠心病的防治有重要意义。

ASSOCIATION BETWEEN THE AGGREGATION OF RISK FACTORS AND CORONARY ARYTERY SEVERITY OF CAD

Objective:To study the relationship of risk factors aggregation and coronary artery severity of coronary atherosclerotic heart disease (CAD).Methods:A correlation studying was carried out in patients that shows positive results in coronary angiogram (at least one artery is narrower than 50%) and their scores about risk factors.Results:The studying shows a positive correlation between thescores of risk factor and coronary artery severity. The studying shows a positive correlation between the quantity of risk factor of CAD and scores of coronary artery severity. The risk degree of individual risk factor was calculated by standard correlation coefficient in turns: Bp, smoking, blood glucose, quantity of exercise,temperament, blood lipids, family history, age and sex, BMI, uric acid, bilirubin,and profession. Aggregation in quanity and degree of risk fact or can increase coronary artery severity degree.Conclusions: Risk factors and their aggregation at individuals are of utmost importance in studying of development, pathophysiological changing, coronary artery sverity quantity and prevention and treatment of CAD.