妊娠期肝内胆汁淤积症胎儿心电监护与围生儿预后

目的　探讨胎儿心电临护无应激试验 (NonStressTest,NST)对预测妊娠期肝内胆汁淤积症 (intra hepaticcholestasisofpregnancy ,ICP)围生儿预后的临床价值。 方法　对 88例ICP和 87例无合并症的正常孕妇进行NST。结果　ICP组NST导常的发生率比正常孕妇组显著增高 (P <0 .0 5 ) ;ICP患者NST异常者与正常孕妇NST异常者比较 ,围生预后不良发生率显著增高 ((P <0 .0 5 ) ;ICP患者NST异常者较NST正常者围生儿预后不良发生率显著增高 (P <0 .0 5 ) ,其特异性为 93.2 % ,敏感性为 6 5 .9% ,阳性预测值为 90 .6 % ,阴性预测值为 73.2 %。结论　NST监测可以了解ICP患者胎儿胎盘功能和预测围生儿的预后 ,具有较高的临床价值。

NST and neonatal prognosis of ICP

Objective:To evaluate clinical value of NST on the neonatal prognosis of ICP.Methods:NST was taken on 88 cases of pregnant women with ICP and 87 cases pregnant women without any complication.Results:The incidence rate of abnormal NST were significantly higher in ICP group than in normal group (P<0.05).The neonatal prognosis was significantly worse in abnormal NST patients of ICP group than in those of normal group. There were significantly worse neonatal prognosis in ICP patients with abnormal NST than those with normal NST (P<0.05).Its specificity was 93.2%,sensitivity was 65.9%,its positive pronostic value was 90.6% and negative value was 73.2%.Conclusions:NST is of much higher clinical value in evaluating placental function and neonatal prognosis.