| 大鼠肝、肾、胰器官簇移植模型的建立水 |
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| 引用本文： | 梁忠平,苏泽轩,丁泓文.大鼠肝、肾、胰器官簇移植模型的建立水[J].中国现代医学杂志,2008,18(23). |
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| 作者姓名： | 梁忠平 苏泽轩 丁泓文 |
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| 作者单位： | 1. 南方医科大学研究生院,广东,广州,510515
2. 暨南大学第一附属医院,广东,广州,510630 |
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| 基金项目： | 广东省自然科学基金(No:04010486) |
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| 摘 要： | 目的 建立大鼠肝、肾、胰器官簇移植模型.方法 106只SPF级Wistar大鼠,按体重进行配对,供者采用腹主动脉和肠系膜上静脉灌洗,摘取肝、胰、十二指肠、右肾及与之相连的腹主动脉和下腔静脉,修整成肝、胰、十二指肠、右肾的器官簇,整块移植到切除肝、右肾的受者腹腔.结果 53次手术中,36次顺利完成,平均手术时间为(4.3±0.6)h,受者大鼠术后存活时间4.1～71.0h.结论 建立大鼠肝、肾、胰器官簇移植模型是可行的.
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| 关 键 词： | 肝 肾 胰器官簇 移植 大鼠 |
Establishment of liver-pancreas-kidney cluster transplantation model |
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| LIANG Zhong-ping
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SU Ze-xuan
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DING Hong-wen.Establishment of liver-pancreas-kidney cluster transplantation model[J].China Journal of Modern Medicine,2008,18(23). |
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| Authors: | LIANG Zhong-ping SU Ze-xuan DING Hong-wen |
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| Institution: | LIANG Zhong-ping1,SU Ze-xuan2,DING Hong-wen2(1.The Post Graduate Department of Southern Medical University,Guangzhou,Guangdong 510515,P.R.China,2.The 1st Affiliated Hospital of the Jinan University,Guangdong 510630,P.R.China) |
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| Abstract: | ObjectiveTo establish the liver-pancreas-kidney cluster transplantation model. MethodsAccording to the principle of the similar weight,40 SPF Wistar rats were allocated into 20 pairs. The donors were irrigated from the abdominal aorta and superior mesenteric vein. Cluster enbloc all splanchnic organs,including liver,pancreas,right kidney,duodenum were procured from the donors and tailored at the back table. The multivisceral cluster were enbloc transplanted to the recipients after the resection of the liver... |
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| Keywords: | liver-pancreas-kidney organ cluster transplantation rat |
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