益气养阴汤治疗病毒性心肌炎的疗效及其对IL-2、PFP的影响

目的 探讨益气养阴汤治疗病毒性心肌炎的作用机制。方法 收集60例病毒性心肌炎病例．随机分为对照组和治疗组，疗程3、4周，治疗前后检测心肌酶学（CK、CK-MB），心脏超声（EF、LVM、LVMI、SO、CO和CI），血清IL-2及淋G细胞穿孔素表达水平（PFP）及疗效评价。结果 应用益气养阴汤治疗病毒性心肌炎EF上升、LVM下降、LVMI下降有统计学意义（P〈0．05）；血清IL-2下降、外周血淋巴细胞穿孔素表达水平下降有统计学意义（P〈0．05）。结论 益气养阴汤治疗病毒性心肌炎有效，免疫作用机制可能与降低外周血IL-2、淋巴细胞穿孔素表达有关。

Therapeutic effect of supplementing qi and nourishing yin soup treat viral myocarditis, and the effect of IL-2 and PFP

[Objective] Initial research the mechanisms of supplementing qi and nourishing yin soup treat viral myocarditis.[Methods] 60 viral myocarditis cases were collected,random divided into control groups and treat group.Course of treatment were 3~4 weeks,every patient examine CK CK-MB EF LVM SO CO CI IL-2 PFP and evaluate therapeutic effect after and before treatment.[Results] Supplementing qi and nourishing yin soup treat viral myocarditis had statistical significance with EF upgrade,with LVM subside and with LVMI subside(P <0.05).The subside of IL-2 and PFP had statistical significance(P <0.05).[Conclusion] Supplementing qi and nourishing yin soup treat viral myocarditis was utility.Immunifaction mechanism may relate with the subside of IL-2 concentration and PFP express level.