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中药板蓝根中高级不饱和脂肪酸的分离鉴定及免疫活性成分的研究
引用本文:秦箐,贺海平,陈鸣.中药板蓝根中高级不饱和脂肪酸的分离鉴定及免疫活性成分的研究[J].中国现代医学杂志,2001,11(1):15-16.
作者姓名:秦箐  贺海平  陈鸣
作者单位:1. 广西医科大学化学教研室
2. 广西肿瘤研究所生化室
3. 丹麦皇家药学院药物化学系
4. 丹麦国家大学医院微生物部
基金项目:中国 -丹麦科技合作协议Danida资助项目!(项目编号AM 9:3),广西教育厅资助项目
摘    要:从十字花科植物菘蓝(Isatis tinctorial L.)的根中首次人鉴定出一组含有三种分子的高级不饱和脂肪酸,命名为板蓝根组酸,并发现其对人多形核细胞(PMN)氧化作用及化学发光具有激活作用,而其邻近流分则具有抑制活性。

关 键 词:板蓝根  板蓝根组酸  人多形核细胞  化学发光

ISOLATION OF HIGHER UNSATURATED FATTY ACIDS AND STUDY OF IMMUNOLOGICALLY COMPETENT CONSTITUENTS FROM ISATIS TINCTORIA L
Qin Jing Chemical Research Center of Guangxi Medical University,Guangxi.ISOLATION OF HIGHER UNSATURATED FATTY ACIDS AND STUDY OF IMMUNOLOGICALLY COMPETENT CONSTITUENTS FROM ISATIS TINCTORIA L[J].China Journal of Modern Medicine,2001,11(1):15-16.
Authors:Qin Jing Chemical Research Center of Guangxi Medical University  Guangxi
Institution:Qin Jing Chemical Research Center of Guangxi Medical University,Guangxi 530021
Abstract:To make isolation of a fraction and its subfractions from'Banlangen',root of Isatis tinctoria L.,and study their immunocompetence.Methods:Afraction 3 and its subfractions were isolated from'Banlangen'with dry-column flash chromato-graphy.It was tested that the effect of those fractions on chemiluminescence(CL) reaction of human polymorphonuclear cells(PMN).Results:A group of higher unsaturated fatty acids that contain three different moleuculse were isolated and elucidated from'Banlan-gen'for the first time and was named Banlangen-acids.A two-way immunocompetence was found form fraction 3 and its subfractins.Conclusion:There are some anti-inflamation components in fraction 3 and its subfractions from'Banlangen'.Banlangen-acids take an important role in it.
Keywords:Isatis Indigotica L  Banlangen-acids  Dry-column Flash Chromatography  Polymorphonuclear(PMN)  Chemiluminescence(CL)
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