经导管室间隔缺损封堵术后左心室收缩功能近、中期变化

目的通过经胸超声心动图（TTE）评价室间隔缺损（VSD）封堵术后左心室收缩功能近、中期变化。方法对该院30例成功施行VSD封堵术治疗患者进行研究。所有患者术前3d内、术后3d、术后3月和术后6月分别进行TTE检查，测量左室舒张末期内径（LVEDD）、左室舒张末期容积（LVEDV）、左室收缩末期容积（LVESV）、左室每搏量（LVSV）、左室射血分数（LVEF）和左室短轴缩短率（LVFS）。结果VSD封堵术后LVEDD、LVEDV、LVESV和LVSV逐渐减少；LVEF和LVFS封堵术后3d、术后3个月和术后6个月较术前下降，而术后3个月、术后6个月与术后3d比较无明显差异。结论VSD封堵术后，伴随左室扩张得到纠正。代偿增强的左心室收缩功能逐渐恢复正常。

Immediate and mid-term changes of left ventricular systolic function after percutanous transcatheter closure of ventricular septal defect

Objective] To study the immediate and mid-term changes of left ventricular systolic function after percutanous transcatheter closure of ventricular septal defect(VSD)by transthoracic echocardiography(TTE).Methods] Thirty patients with VSD successfully underwent trascatheter VSD closure.TTE was performed before and in 3 days,3 months,6 months after closure respectively.The left ventricular end-diastolic diameter(LVEDD),left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular stroke volume(LVSV),left ventricular ejection fraction(LVEF)and left ventricular fractional shortening(LVFS)were obtained.Results] The LVEDD,LVEDV,LVESV and LVSV were gradually reduced after closure significantly.The LVEF and LVFS were lower in 3 days,3 months and 6 months after closure than before,while no evident difference was found among in 3 days,3 months and 6 months after closure.Conclusion] After VSD closure compensative enhanced left ventricular systolic function gradually became normal in pace with the correctness of left ventricular enlargment.