| 肝气郁结证病理生理学基础研究 |
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| 引用本文： | 陈泽奇,陈国林,金益强,黎杏群,李家邦,胡随瑜,赵玉秋,石林阶,李学文,张翔,陈昌华,鄢东红.肝气郁结证病理生理学基础研究[J].中国现代医学杂志,2000,10(10):21-23,26. |
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| 作者姓名： | 陈泽奇 陈国林 金益强 黎杏群 李家邦 胡随瑜 赵玉秋 石林阶 李学文 张翔 陈昌华 鄢东红 |
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| 作者单位： | 湖南医科大学附属湘雅医院中西医结合研究所,410008 |
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| 基金项目： | 国家自然科学基金重点资助课题!(39330 2 40 ) |
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| 摘 要： | 为了研究肝气郁结证的病理生理学基础，对１５０例肝气郁结证患者进行了多指标检测。结果表明肝气郁结证患者植物神经功能紊乱，血浆ＮＥ、Ｅ平均含量接近正常，但不同精神状态含量变化较大。血浆ｃＧＭＰ、ＴＸＢ２、ＴＸＢ２／６－Ｋｅｔｏ－ＰＧＦ１α比值、ＡＶＰ含量较健康人显著升高。血浆ｃＡＭＰ／ｃＧＭＰ比值、６－Ｋｅｔｏ－ＰＧＦ１α、Ｌ－ＥＮＫ、ＡＮＰ及血清胃泌素含量显著降低。结果提示肝气郁结证与中枢神经对情绪调节的功能异常密切相关。
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| 关 键 词： | 肝气郁结证 植物神经功能 环核苷酸 病理 |
STUDIES ON THE PATHOPHYSIOLOGICAL BASIS OF THE LIVERQI STAGNATION SYNDROME |
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| Chen Zeqi,Chen Guolin,Jin Yiqiang,et al..STUDIES ON THE PATHOPHYSIOLOGICAL BASIS OF THE LIVERQI STAGNATION SYNDROME[J].China Journal of Modern Medicine,2000,10(10):21-23,26. |
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| Authors: | Chen Zeqi Chen Guolin Jin Yiqiang |
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| Institution: | Chen Zeqi,Chen Guolin,Jin Yiqiang,et al. The institute of intergrated TCM and WM of Xiangya Hospital,Hunan Medical University,Changsha 410008 |
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| Abstract: | Objective To investigate the
pathophysiological basis of the syndrome of Liver―Qi stagnation. Methods We determined several indices in 150 patients. Results
the Vegetative nervous functions were disordered. The average contents of plasna NE.E were
similar between the patients and helthy subject, but there were different contents
according to the different mental condition. The plasma Contents of cGMP, TXB2, AVP and
the ratio TXB2/6-Keto-PGF1α in patients were
obviously higher than that of healthy subjects. The plasma contents of the ratio
cAMP/cGMP, 6-Keto- PGF1α L-ENK, ANP and
serum contents of gastrin were decresed than that of the healthy subjects. Conclusions
the syndrome of Liver-Qi stagnation has a direct correlation on the function of regulating
emotion of the central nervous system. |
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| Keywords: | Syndrome of Liver-Qi Stagnation Vegetative Nervous Function Cyclic Nucleotide Norepinephrine Epinephrine Thromboxane Leucine-Enkephalin Argimine Vasopresin Atrial Natruretic Polypetides Pathophysiology |
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