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SD大鼠肺炎链球菌致病的临床及病理观察
引用本文:周智君,俞远京,晏群,苏志杰.SD大鼠肺炎链球菌致病的临床及病理观察[J].中国现代医学杂志,2004,14(22):59-60.
作者姓名:周智君  俞远京  晏群  苏志杰
作者单位:1. 中南大学湘雅医学院,实验动物学部,湖南,长沙,410078
2. 中南大学湘雅医院,检验科,湖南,长沙,410008
基金项目:湖南省实验动物专项基金
摘    要:目的对SD大鼠肺炎链球菌致病进行观察。方法通过流行病学观察、临床症状观察、病理组织检查、微生物学检查,观察了大鼠肺炎链球菌致病的情况。结果大鼠肺炎链球菌致病SD大鼠食欲减退、精神不振、鼻孔带血和呼吸困难;慢性间质性肺炎、肺气肿;呼吸道细菌培养出肺炎链球菌。结论成功地观察了SD大鼠肺炎链球菌致病的情况。

关 键 词:SD大鼠  肺炎链球菌病
文章编号:1005-8982(2004)22-0059-02

Clinic symptoms and pathological observation of SD rat infected by streptococcus pneumoniae
ZHOU Zhi-jun ,YU Yuan-jing ,YAN Qun ,SU Zhi-jie.Clinic symptoms and pathological observation of SD rat infected by streptococcus pneumoniae[J].China Journal of Modern Medicine,2004,14(22):59-60.
Authors:ZHOU Zhi-jun  YU Yuan-jing  YAN Qun  SU Zhi-jie
Institution:ZHOU Zhi-jun 1,YU Yuan-jing 1,YAN Qun 2,SU Zhi-jie 1
Abstract:Objective:To observe the disease of SD rat caused by streptococcus pneumoniae.Methods:Epidemic characteristics,clinic symptoms and pathologic examination were used.Results:The infected rats had anorexia,psy-chasthenic,nose bleeding and difficult breathing;chronic interstitial pneumonia,pulmonary emphysema were mani-fested;the bacterial culture of secretion from respiratory tract was positive.Conclusions:We have successfully ob-served the SD rat infected by streptococcus pneumoniae.
Keywords:SD Rat  streptococcus pneumoniae
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