| 肉毒毒素A治疗偏侧面肌痉挛临床观察(附150例报告) |
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| 引用本文： | 亓法英,周广福,赵孔波.肉毒毒素A治疗偏侧面肌痉挛临床观察(附150例报告)[J].中国现代医学杂志,2002,12(3):43-44. |
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| 作者姓名： | 亓法英 周广福 赵孔波 |
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| 作者单位： | 1. 解放军146医院神经内科,276000
2. 山东临沂市人民医院急救中心,276001 |
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| 摘 要： | 目的 :研究面肌痉挛的发病机制 ,观察肉毒毒素A治疗面肌痉挛的疗效。方法 :对 15 0例HFS病人进行面部多点肌肉注射肉毒毒素A ,复发者重复注射。部分病人行MRA和EMG检查。结果 :76例完全缓解 ,6 2例明显缓解 ,9例部分缓解 ,3例无效。重复注射后 ,总有效率 94 % ,2 4例出现副作用短时恢复。结论 :肉毒毒素A局部注射治疗面肌痉挛是一种安全有效的方法。
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| 关 键 词： | 偏侧面肌 痉挛 肉毒毒素A 疗效 |
| 修稿时间： | 2001年1月18日 |
CLINICAL OBSERVATION OF BOTULINUM TOXIN A IN TREATMENT FOR 150 CASES OF HEMIFACIAL SPASM |
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| Qi Faying,Zhou Guangfu,Zhao Kongbo.CLINICAL OBSERVATION OF BOTULINUM TOXIN A IN TREATMENT FOR 150 CASES OF HEMIFACIAL SPASM[J].China Journal of Modern Medicine,2002,12(3):43-44. |
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| Authors: | Qi Faying Zhou Guangfu Zhao Kongbo |
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| Institution: | Qi Faying,Zhou Guangfu,Zhao Kongbo Department of Neurology,The 146th Hospital of PLA,Linyi,Shandong 276000 |
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| Abstract: | Objective:To determine the pathogeny of hemifacial spasm (HFS) and evaluate the therapeutic efficacy of botulinum A.Methods:150 HFS patients received multifocal facial injection with botulinum A.The recrudesences were repeat injection.EMG and MRA were performed in partial patients.Results:Seventy-six patients (50.7%) were cured;sixty_two (41.3%) were significantly improved;nine (6%) were partly improved;three were not improved.The total cure rate was 94% after repeated injection in some cases.Side effects were minor and transient,althought occurred in twenty_four.Conclusions:Our results provide a further evidence for the efficacy of local injection of botulinum toxin A in the treatment for hemifacial spasm. |
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| Keywords: | Hemifacial Sapasticity Botulinum toxin A Efficacy |
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