淋巴细胞脉络丛脑膜炎病毒感染实验动物的情况概述

淋巴细胞脉络丛脑膜炎病毒(lymphocytic chorimeningtis virus,LCMV)能广泛感染啮齿类动物和人,是一种重要的人畜共患病病原。近些年LCMV感染人的检测得到加强,在实验动物中的感染率一直控制在较低水平。我国的实验动物国家标准要求豚鼠、地鼠必需检测LCMV,小鼠只在必要时检测,而国外普遍要求对大鼠等动物也作为常规检测项目。为了提高对实验动物感染LCMV的检测意识,本文对不同国家和地区LCMV感染实验动物的情况做一综述。

A short introduction on infection of lymphocytic chorimeningtis virus in laboratory animals

Abstract: lymphocytic choriomeningitis Virus (LCMV) is a significant zoonosis. Recently, human infected with lymphocytic chorimeningtis virus (LCMV) are diagnosed more efficient. LCMV infection rate of laboratory animals is regulated at the low level. In Chinese national standards, LCMV is a required test item for guinea pigs and hamsters, but for mice only test when it necessary. However, LCMV is a routine test item for rats in some other areas. To strengthen the awareness of LCMV test, we will introduce information about laboratory animals LCMV infection status in different countries and areas.