豚鼠遗传检测方法研究进展

豚鼠作为一种常用的实验动物，广泛应用于生物医学研究中的各个领域，其遗传质量的稳定性直接影响着它的发展和应用。遗传检测目的是为了证实各品系动物应具有的遗传特性，检查是否发生遗传污染和遗传突变等，确保被检对象符合该品系的要求。生化标记和分子标记技术的出现，为实验豚鼠基因纯合度、遗传类型检测、遗传质量监测提供了更为简便可靠的研究手段。本文就生化标记、细胞学标记和分子标记在豚鼠多样性研究中的应用及研究进展进行了论述，为豚鼠遗传检测方法的建立提供帮助。

The Research Development of Genetic Monitor Methods In Guinea Pig

Guinea pig as a commonly used laboratory animal is widely used in various fields of biomedical research. The stability of genetic quality directly affects its development and application. Genetic testing is designed to confirm the genetic characteristics of each strain, to verify whether there are genetic mutations and other genetic contamination, to ensure that the test object meets the requirements of this strain. Along with the emerge of biochemical and molecular marker technology, a more convenient and reliable means is provided for research of genetic homozygosity, genetic type detection and genetic quality monitoring of guinea pigs. In this paper, the application and research progress of biochemical, cytological and molecular markers in studies of guinea pig diversity will be summarized, and provide some help for genetic testing guinea pig.