Clinical Efficacy and Molecular Mechanism of Nourishing Shen and Supplementing Marrow Principle in Treating β Thalassemia |
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引用本文: | 吴志奎,方素萍,张新华,蔡辉国,王蕾,易杰,柴立民,吕鑫霞,陈玉英,黄有文,王荣新,陈佩珍.Clinical Efficacy and Molecular Mechanism of Nourishing Shen and Supplementing Marrow Principle in Treating β Thalassemia[J].Chinese Journal of Integrated Traditional and Western Medicine,2003,9(4). |
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作者姓名: | 吴志奎 方素萍 张新华 蔡辉国 王蕾 易杰 柴立民 吕鑫霞 陈玉英 黄有文 王荣新 陈佩珍 |
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作者单位: | Department of Molecular Biology,Guang'anmen Hospital,China Academy of Traditional Chinese Medicine,Department of Molecular Biology,Guang'anmen Hospital,China Academy of Traditional Chinese Medicine,Institute of Hematology,Chinese Academy of Medical Sciences,Department of Molecular Biology,Guang'anmen Hospital,China Academy of Traditional Chinese Medicine,Department of Molecular Biology,Guang'anmen Hospital,China Academy of Traditional Chinese Medicine,Department of Molecular Biology,Guang'anmen Hospital,China Academy of Traditional Chinese Medicine,Department of Molecular Biology,Guang'anmen Hospital,China Academy of Traditional Chinese Medicine,Department of Molecular Biology,Guang'anmen Hospital,China Academy of Traditional Chinese Medicine,The 303 Hospitol of PLA,The 303 Hospitol of PLA,Institute of Hematology,Chinese Academy of Medical Sciences BeiJing (100053),BeiJing (100053),BeiJing (100053),BeiJing (100053),BeiJing (100053),BeiJing (100053),BeiJing (100053) |
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基金项目: | This item was supported by National Funds of Natural Sciences (No. 3017119 9) and Natural Science Foundation of Guangxi Autonomous Region (No. 014402C) |
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摘 要: | βthalassemiaisakindofhereditaryhemolyticanemia,whichspreadsextensivelyalongthecoastalcountriesoftheMediterraneanSea.InChina,thein cidentofthediseaseisrelativelyhighinthesouthernprovincesandthehighestinGuangxiZhuangAu tonomousRegion,YunnanandGuizhouProvinces(2 % - 4.5 %).Themolecular pathogenesisisblamedonβgenedefectorinability,γgeneincapabili tyofinitiation,andglobinsynthesisincompetence,whichcouldresultinearlystagehematopoieticdisor der.Thediseaseisharmful,theprognosisoftheseveretypeis…
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关 键 词: | nourishing Shen and supplementing marrow principle Shen producing marrow β-thalassemia gene analysis mRNA gene ex pression molecular mechanism |
Clinical Efficacy and Molecular Mechanism of Nourishing Shen and Supplementing Marrow Principle in Treating β-Thalassemia |
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Authors: | WU Zhi kui FANG Su ping ZHANG Xin hua CAI Hui guo WANG Le i Yi Jie Chai Li min LU Xin xia CHEN Yu ying HUANG You wen WANG Rong xin and CHEN Pei zhen |
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Keywords: | nourishing Shen and supplementing marrow principle Shen producing marrow gene analysis mRNA gene expression molecular mechanism |
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