Effects of 24 Chinese Medicinal Herbs on Nucleic Acid, Protein and Cell Cycle of Human Lung Adenocarcinoma Cells

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Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells

Objective: To study the effects of 24 Chinese medicinal herbs on nucleic acid, protein and cellcycle of human lung adenocarcinoma cells. Methods: Using flow cytometry the authors analysed the effects of 24Chinese medicinal herbs (CMH) in compound recipe on proliferation index (PI), DNA index, protein index andratio of various phases in cell cycle of human lung adenocarcinoma cells (SPC-A-1). Results: The PI was morethan 20%, in 4 CMH, while 3 CMH, Gynostemma Pentaphylla, Radix Glehnia, and Radix Ginseng couldstrengthen the body resistance. That suggested using CMH of strengthening body resistance could not only serveas conventional ionic but also as tumor cell inhibitor. Meanwhile the action points of 24 CMH on cell cycle weredifferent from one another. Conclusions: According to these results, Chinese recipes were more effective in clinical practice.