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| D3S1358、vWA和FGA基因座在河南回族群体中的遗传多态性分析 | |
| 引用本文： | 黄书琴,申成斌,朱运良,相志德,杜月丛.D3S1358、vWA和FGA基因座在河南回族群体中的遗传多态性分析[J].河南医学研究,2003,12(3):213-215. |
| 作者姓名： | 黄书琴 申成斌 朱运良 相志德 杜月丛 |
| 作者单位： | 1. 郑州市公安局刑事科学技术研究所,河南郑州,450000 2. 河南省公安厅刑事科学技术研究所,河南郑州,450003 3. 中山大学中山医学院法医系,广东广州,510000 |
| 摘 要： | 目的 :了解D3S13 5 8、vWA和FGA基因座多态性在河南回族群体中的分布特点及其应用价值。方法 :使用荧光自动检测技术。结果 :D3S13 5 8基因座检出 7个等位基因 (n =15 1) ,vWA基因座检出 7个等位基因(n =15 1) ,FGA基因座检出 13个等位基因 (n =14 9) ,三个位点的等位基因频率在群体中的分布符合Hardy Weinberg平衡。结论 :D3S13 5 8、vWA和FGA三个遗传标记的个人识别率高、非父排除能力较强且能稳定遗传 ,具有较高的应用价值 |
| 关 键 词： | 短串联重复序列 D3S1358 vWA FGA 遗传多态性 |
| 文章编号： | 1004-437X(2003)03-0213-03 |
| 修稿时间： | 2003年4月30日 |
Genetic polymorphism of D3S1358,vWA and FGA locus in Hui population in Henan |
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| HUANG Shu-qin ,SHEN Cheng-bin ,ZHU Yun-liang ,?XIANG Zhi-de ,DU Yue-cong.Genetic polymorphism of D3S1358,vWA and FGA locus in Hui population in Henan[J].Henan Medical Research,2003,12(3):213-215. | |
| Authors: | HUANG Shu-qin SHEN Cheng-bin ZHU Yun-liang ?XIANG Zhi-de DU Yue-cong |
| Institution: | HUANG Shu-qin 1,SHEN Cheng-bin 2,ZHU Yun-liang 3,?XIANG Zhi-de 1,DU Yue-cong 1 |
| Abstract: | Objective: To obtain the alleles frequencies and data of three STR loci(D3S1358、vWA and FGA) in Hui population living in Henan.Methods: The PCR products were analyzed by fluorescent detection.Results: 7 alleles and 16 genotypes were observed at D3S1358 locus,7 alleles and 23 genotypes were observed at vWA locus,13 alleles and 44 genotypes were observed at FGA locus.The alleles frequencies of three loci revealed no deviation from the Hardy-Weinberg equilibroum.Conclusion: The three loci(D3S1358、vWA and FGA)were proved to be highly discrimination and useful in the fields of individual identification and paternity diagnosis. |
| Keywords: | short tandem repeats D3S1358 vWA FGA genetic polymorphism |
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