| 血小板活化因子与冠状动脉病变支数相关性研究 |
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| 引用本文： | 海祺旻,沈德良,刘琮琳,张金盈.血小板活化因子与冠状动脉病变支数相关性研究[J].河南医学研究,2014,23(1):19-21. |
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| 作者姓名： | 海祺旻 沈德良 刘琮琳 张金盈 |
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| 作者单位： | 海祺旻 (郑州大学第一附属医院心血管内科 河南郑州 450052河南省高等学校临床医学重点学科开放实验室 河南郑州 450052)； 沈德良 (郑州大学第一附属医院心血管内科 河南郑州 450052)； 刘琮琳 (郑州大学第一附属医院心血管内科 河南郑州 450052河南省高等学校临床医学重点学科开放实验室 河南郑州 450052)； 张金盈 (郑州大学第一附属医院心血管内科 河南郑州 450052)； |
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| 摘 要： | 目的:探讨冠脉造影患者血小板活化因子(platelet-activating factor,PAF)水平与冠状动脉病变支数的相关性。方法:将128例可疑冠心病患者按冠脉造影结果分为:健康对照组(21例)、冠心病组(107例)。冠心病组记录冠脉病变支数。用酶联免疫法(ELASA)测量血浆PAF浓度,分析其与冠状动脉病变支数的相关性。结果:PAF浓度与冠状动脉病变支数呈正相关,差异有统计学意义(P<0.05)。结论:PAF浓度水平有望作为冠心病病情监测的指标。
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| 关 键 词： | 冠心病 冠状动脉狭窄 血小板活化因子 冠脉造影 |
Correlation between platelet-activating factor and the number of stenosed coronary vessels |
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| HAI Qimin,SHEN Deliang,LIU Conglin,ZHANG Jinying.Correlation between platelet-activating factor and the number of stenosed coronary vessels[J].Henan Medical Research,2014,23(1):19-21. |
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| Authors: | HAI Qimin SHEN Deliang LIU Conglin ZHANG Jinying |
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| Institution: | 1. Department of Cardiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China ; 2. Institute of Clini- cal Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China) |
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| Abstract: | Objective： To investigate the correlation between platelet-activating factor（PAF） and the number of stenosed coronary vessels in patients with coronary angiography （ CAG）. Methods ： 128 cases with suspected CHD were divided into groups according to coronary angiography, including 21 normal cases, 107 patients with CHD, whose number of stenosed coronary vessels was recorded. The PAF concentrations were detected by ELISA, and the relationship between PAF concentrations and the number of stenosed coronary vessels was analyzed. Results： There were positive correlations between the PAF levels and the number of stenosed coronary vessels, the differences were statistically significant （P 〈 0. 05 ）. Conclusion ： PAF concentrations are related with the degree of coronary artery stenosis and may serve as an available index for the severity of CHD. |
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| Keywords: | coronary disease coronary stenosis platelet-activating factor coronary angiography |
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