腰椎间盘突出症不同阶段NO、IL-6与腰椎功能的相关性研究

目的：探讨腰椎间盘突出症不同阶段NO、IL-6与腰椎功能的相关性。方法：随机抽取腰椎间盘突出症患者400例,根据治疗方法不同分为整复手法A组（恢复期采用整复手法）、整复手法B组（缓解期采用整复手法）、推拿组和西药组,每组100例。3个月后,分别检测不同方法不同时期血NO、IL-6含量,并分析与ODI分值、RMDQ分值的相关性。结果：NO与ODI分值、RMDQ分值相关性分析显示,整复手法A组、整复手法B组、推拿组、西药组急性期血NO含量与ODI分值、RMDQ分值呈正相关,差异有统计学意义（P〈0.05）;IL-6含量与ODI分值、RMDQ分值相关性分析显示,整复手法A组、整复手法B组、推拿组、西药组急性期血IL-6含量与ODI分值、RMDQ分值呈正相关,差异有统计学意义（P〈0.05）。结论：腰椎间盘突出症各期NO、IL-6与腰椎活动功能呈正相关。

Correlation between Lumbar Function and NO,IL-6 at Different Stages of Differentiation Therapy of Lumbar Disc Herniation

Objective： To explore the correlation between lumbar function and NO,IL-6 at different stages of differentiation therapy of lumbar disc herniation. Methods： 400 patients with lumbar herniated disc in rehabilitation department were involved. They were divided into the reduction technique of group A（ recovery using reduction technique）,the reduction manipulation of group B（ remission using reduction manipulation）,massage group and western medicine group according to the different treatment techniques,and 100 patients in each group. Three months later,the correlation between lumbar function and NO,IL-6 at different stages of differentiation therapy of lumbar disc herniation were analyzed. Results： In acute phase serum NO content and ODI scores,RMDQ scores were positively correlated in group A,group B,massage group and western medicine group. The difference was statistically significant（ P〈0. 05）. In acute phase serum IL-6 content and ODI scores,RMDQ scores were positively correlated in four groups. The difference was statistically significant（ P〈0. 05）. Conclusion： NO,IL-6 and lumbar function are positively correlated in the phases of lumbar disc herniation.