肝炎肝硬化中医证型与垂体甲状腺轴激素的相关性研究

目的:在辨证与辨病相结合的基础上探究垂体甲状腺轴激素指标与肝炎后肝硬化辨证分型的相关性.方法:选取120例肝炎肝硬化患者进行辨证分型,分组检测T,3、T,4、rT,3、FT,3、FT,4及TSH水平与正常对照组30例相应指标进行比较.结果:脾虚湿盛、湿热内蕴、脾肾阳虚组T,3、FT,3降低及rT,3升高较肝肾阴虚组、肝气郁结组、对照组具有显著性差异;脾肾阳虚组T,4、FT,4较肝肾阴虚组、肝气郁结组、对照组明显降低;5个证型的TSH之间的变化无显著性差异.结论:血清垂体甲状腺轴激素与肝硬化中医证型具有一定的相关性.

The Dependability of Chinese Medicine Type of Syndrome and Pituitary-Thyroid Axis in Hepatitis Cirrhosis

Objective: to approach the dependability of Chinese medicine type of syndrome and pituitary-thyroid axis in hepatitis cirrhosis. Method: the T3,T4,rT3,FT3,FT4 and TSH were detected in control and treatment. Results: the t3 and FT3 degrade and rT3 high in damp abundance due to splenic asthenia,endoretention of damp heat and asdthenic splenonephro-yang. It has significant difference compare with hepatic and renal yin deficiency,stagnation of liver-qi and control. The T4 and FT4 were degraded in asdthenic splenonephro-yang. It has significant difference compare with hepatic and renal yin deficiency,stagnation of liver-qi and control. The TSH has no significant difference. Conclusion: there are some dependability between pituitary-thyroid axis hormone and Chinese medicine type of syndrome of cirrhosis.