| 铅性肾损害效应生物标志物β2-MG、NAG、RBP的相关影响因素研究 |
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| 引用本文： | 苏素花,蒋东方,农康,廖瑞庆.铅性肾损害效应生物标志物β2-MG、NAG、RBP的相关影响因素研究[J].中国医学文摘：老年医学,2009(12):1239-1242. |
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| 作者姓名： | 苏素花 蒋东方 农康 廖瑞庆 |
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| 作者单位： | 广西壮族自治区职业病防治研究院,南宁530021 |
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| 基金项目： | 基金项目：广西壮族自治区科学技术厅自然基金项目（编号：200104） |
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| 摘 要： | 目的研究β2-MG、NAG、RBP在铅性肾损害评价中的影响因素。方法采用相关分析或分组比较法。结果β2-MG、NAG、RBP与年龄、接铅工龄呈明显正相关（r依序为：0．221、0．230、0．433，0．359、0．419、O．365），β2-MG、RBP与血铅呈明显正相关（r依序为：O．419、0．354）；另外三个指标间也有明显相关关系。结论应用RBP、β2-MG、NAG评价铅性肾损害时，应注意个体的年龄、接铅工龄的影响，并注意与血铅及其各指标间的相互关系。
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| 关 键 词： | 铅性肾损害 β2-MG NAG RBP 影响因素 |
Study on the influential factors of the β2-MG,NAG and RBP evaluating the nephrotoxicity caused by lead |
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| Institution: | SU Su-hna, JIANG Dong-fang, NON Kang,et al( Guangxi Initute of Occupational Disease, Nanning 530021, China) |
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| Abstract: | Objective To study the influential factors of the β2-MG,NAG and RBP evaluating the nephro- toxicity caused by lead. Methods In the study, the methods of the correlation analysis and group comparison were a- dopted. Results The data of the β2-MG, NAG and RBP are related to the age and receptive-lead standing （ r=0. 221,0. 230,0. 433,0. 359,0. 419,0. 365 ）. And the data of β2-MG and RBP related to the PbB （ r= 0. 419, 0. 354）. Moreover, the relations among the β2-MG,NAG and RBP were existing. Conclusion When the β2-MG, NAG and RBP are used to evaluate the nephrotoxieity caused by lead, the indexes are influenced by the age, receptive-lead standing and PbB. |
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| Keywords: | Nephrotoxicity caused by lead β2-MG NAG RBP Influential factors |
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