慢性肝性脑脊髓病头部MRI表现与临床研究

目的 研究慢性肝性脑脊髓病在头部MRI上的特点。方法 本组观察21例慢性肝性脑脊髓病病人，全部病人均符合慢性肝性脑病和慢性肝性脊髓病的诊断；并且均做头部MRI、肝功能和血氨等检查。结果 21例头部MRI显示有苍白球T1W1高信号改变，这种异常信号可以随肝脏功能变化和肝脏脑病的改善而改善，与血氨的浓度变化无关。结论 慢性肝性脑病病人头部MRI显示苍白球T1W1高信号，其发生与长期肝硬变及门脉分流导致肝的代谢异常有关。

Clinical research on brain MRI of chronic hepatic encephalopathy and myelopathy

Objective To research into the character of MRI of brain in chronic hepatic encephalopathy and myelopathy.Methods To observe 21 cases of chronic hepatic encephalopathy and myelopathy,all of them accord with the diagnostic criteria.MRI of brain?liver function?blood ammonia?ultrasonic examination and so on were taken for all cases.Results In all patients with hepatocirrhosis MRI showed T(1) weighted magnetic resonance signal hyperintensities in pallidum (100%),secondly in midbrain (23.8%) and pons (9.5%).This signal density changed into light following the liver function and hepatic encephalopathy improved.Conclusions This signal was related to hepatic metabolic abnormality after hepatocirrhosis and portal vein shunt.