血浆粘度与胃粘膜血流关系的研究

目的　研究血浆粘度对胃粘膜血流的影响。方法　选择无心血管、肝、肾及内分泌系统疾病的慢性胃炎患者 80例 ,用激光多普勒血流仪测定病人胃粘膜血流 (GMBF) ,同时检测病人血流变学各指标。结果　老年人GMBF明显低于年轻人 (P<0 .0 1) ,老年人血浆粘度 (BV)比年轻人高 (P<0 .0 5 ) ,且与胃粘膜血流呈负相关。结论　血浆粘度直接影响胃微循环灌注 ,且随年龄增加而升高 ,这可间接影响胃粘膜的修复和愈合 ,在胃肠疾病的治疗中 ,血浆粘度不容忽视 ,它是引起老年人胃粘膜血流下降的原因之一。

Study on the relationship between plasma viscosity and gastric mucosal blood flow

Objective To study the effect of plasma viscosity on the gastric mucosa blood flow (GMBF).Methods To select 80 cases of patients with chronic gastritis,without cardio vascular,liver,renal and endocrine diseases.To measure GMBF with laser Doppler Flowmenry and measure blood theological parameters.Results Plasma viscosity is higher in the elder than in the youngster,but GMBF is lower in the elder than in the young ster.There was a negative correlation between the plasma viscosity and GMBF.Conclusion Plasma viscosity effect directly microcirculation of the stomach increases with age.This may affect indirectly gastric mucosa repair and healing.In the treatment of gastric disease plasma viscosity should not be neglected.