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偏头痛患者血浆与脑脊液内皮素1含量的变化与临床意义
引用本文:陈恒年,匡培根.偏头痛患者血浆与脑脊液内皮素1含量的变化与临床意义[J].北京医学,1994,16(2):65-68.
作者姓名:陈恒年  匡培根
作者单位:中国人民解放军251医院神经内科,中国人民解放军总医院脑系科
摘    要:本文报道了20例偏头痛患者血浆与脑脊液(CSF)内皮素1(ET1)含量的变化与临床意义。发现偏头痛患者血浆及CSF的ET1含量在发作期均显著高于对照组。但血浆与CSF的ET1含量不论在偏头痛患者组或对照组均无相关性。CSF的ET1含量与头痛的严重程度有关,者显著高于轻、中度者。还发现偏头痛患者伴随面色苍白者,其血浆ET1含量显著高于不伴苍白者。本文对偏头痛的发痛机理,血浆及CSF ET1含量增高的

关 键 词:偏头痛  血浆  脑脊液  内皮素

Changes of plasm and CSF ET_1 in migraine and their clinical significance
Chen Hengnian,et al.Changes of plasm and CSF ET_1 in migraine and their clinical significance[J].Beijing Medical Journal,1994,16(2):65-68.
Authors:Chen Hengnian  
Abstract:The purpose of this study is to explore the relation between migraine and endotheliun (ET1) and twenty migraine patients were included in this study.It was found that both the CSF and plasma ET1 concentrations in migraine patients were significently higher than those of controls. Nocorrelative relationships ET1 about concentrations were found in plasma and CSF in both groups. The CSF ET1 concentration in migraine patients with severe headache was significantly higher than that in patients with mild and moderate headache. The plasma ET1 concentration in patients with facial pallor was significantly higher than that in patients without facial pallor.The pathogenesis of migraine, the cause and clinical implications of the increase of ET1 are discussed.
Keywords:Migraine  Plasm  CSF  ET1
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