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USING CRYOPRESERVED HOMOGRAFT PERICARDIAL PATCH IN STAGED COMPLETE REPAIR FOR TETRALOGY OF FALLOT
作者姓名:孙彦隽  张海波  刘锦纷  苏肇伉  徐志伟  曹鼎方
作者单位:Department of Pediatric Thoracic and Cardiovascular Surgery, Shanghai Children's Medical Center, School of Medicine,Shanghai Jiaotong University, Shanghai 200127, China
摘    要:Objective To compare the difference of effect while using homograt pericardium patch and Gore-rex patch in staged complete repair for Tetralogy of Fallot (TOF) to enlarge the right ventricular outflow tract (RVOT). Methods Twenty-eight patients with TOF underwent the staged complete repair. Gore-rex patches were used to enlarge the RVOT of 13 patients, and cryopreserved homograft pericardium patches were used to enlarge the RVOT of 15 patients. The patients were followed up with 2-dimensional echocardiography and chest x-ray. Results One operative death in Gore-rex patch group, the mortality was 7. 7% ; 1 early postoperative death in cryopreserved homograft pericardium patch group, the mortality was 6. 7%. Between 2 groups, hemostasia time in operation room with significant difference ( P 〈 0. 01 ), pericardial cavity drainage volume with difference ( P 〈 0. 05 ). Gore-rex patch group was followed up 2 to 4.5 years, homograft pericardium patch group was followed up 0. 8 to 2.1 years. Echocardiography showed that there was significant difference of the residual obstruction at RVOT level ( P 〈 0. 01 ). No calcification shadow was discovered on the chest x-ray of both groups. Conclusion Homograft pericardium is tissue with high density and intensity, its elasticity and compliance are good. Using homograft pericardium patch maybe helpful to decrease the residual obstruction of RVOT after operation. It can be adapted as a repairing material in cardiac surgery.

关 键 词:心包疾病  同种移植  手术治疗  心室肿瘤
收稿时间:2005-01-14

USING CRYOPRESERVED HOMOGRAFT PERICARDIAL PATCH IN STAGED COMPLETE REPAIR FOR TETRALOGY OF FALLOT
SUN Yan-juan, ZHANG Hai-bo, LIU Jin-fen, SU Zhao-kang, XU Zhl-wel, CAO Ding-fang.USING CRYOPRESERVED HOMOGRAFT PERICARDIAL PATCH IN STAGED COMPLETE REPAIR FOR TETRALOGY OF FALLOT[J].Journal of Shanghai Second Medical University(Foreign Language Edition),2006,18(1):60-63.
Authors:SUN Yan-juan  ZHANG Hai-bo  LIU Jin-fen  SU Zhao-kang  XU Zhl-wel  CAO Ding-fang
Abstract:Objective To compare the difference of effect while using homograt pericardium patch and Gore-tex patch in staged complete repair for Tetralogy of Fallot ( TOF) to enlarge the right ventricular outflow tract (RVOT). Methods Twenty-eight patients with TOF underwent the staged complete repair. Gore-tex patches were used to enlarge the RVOT of 13 patients, and cryopreserved homograft pericardium patches were used to enlarge the RVOT of 15 patients. The patients were followed up with 2-dimensional echocardiography and chest x-ray. Results One operative death in Gore-tex patch group, the mortality was 7. 7% ; I early postoperative death in cryopreserved homograft pericardium patch group, the mortality was 6. 7%. Between 2 groups, hemostasia time in operation room with significant difference ( P < 0. 01) , pericardial cavity drainage volume with difference (P < 0.05). Gore-tex patch group was followed up 2 to 4.5 years, homograft pericardium patch group was followed up 0. 8 to 2. 1 years. Echocardiography showed that there was significant difference of the residual obstruction at RVOT level (P < 0. 01). No calcification shadow was discovered on the chest x-ray of both groups. Conclusion Homograft pericardium is tissue with high density and intensity, its elasticity and compliance are good. Using homo-graft pericardium patch maybe helpful to decrease the residual obstruction of RVOT after operation. It can be adapted as a repairing material in cardiac surgery.
Keywords:tetralogy of Fallot homograft pericardium cardiac surgery
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